相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge
Nathan L. Pollesch et al.
TOXICOLOGICAL SCIENCES (2019)
Adverse Outcome Pathways: Moving from a Scientific Concept to an Internationally Accepted Framework
Markus Hecker et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2019)
An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity
Jinpeng Li et al.
NEUROTOXICOLOGY (2019)
An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments
Victor Gonzalez-Ruiz et al.
METABOLITES (2019)
A Modular Approach for Assembly of Quantitative Adverse Outcome Pathways
Christy M. Foran et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2019)
Chemical Hazard Prediction and Hypothesis Testing Using Quantitative Adverse Outcome Pathways
Edward J. Perkins et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2019)
WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research
Denise N. Slenter et al.
NUCLEIC ACIDS RESEARCH (2018)
Adverse outcome pathway networks II: Network analytics
Daniel L. Villeneuve et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2018)
Adverse outcome pathway networks I: Development and applications
Dries Knapen et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2018)
Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways
Daniel L. Villeneuve et al.
TOXICOLOGICAL SCIENCES (2018)
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
Ellen Fritsche et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2018)
Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods
Anna Bal-Price et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2018)
Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity
Anna Bal-Price et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2018)
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities
Bela Z. Schmidt et al.
ARCHIVES OF TOXICOLOGY (2017)
Using In Vitro High-Throughput Screening Data for Predicting Benzo[k] Fluoranthene Human Health Hazards
Lyle D. Burgoon et al.
RISK ANALYSIS (2017)
Reference Compounds for Alternative Test Methods to Indicate Developmental Neurotoxicity (DNT) Potential of Chemicals: Example Lists and Criteria for their Selection and Use
Michael Aschner et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2017)
Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment
Kembra L. Howdeshell et al.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2017)
Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity
Anna Bal-Price et al.
NEUROTOXICOLOGY (2017)
Adverse outcome pathways: Application to enhance mechanistic understnding of neurotoxicity
Anna Bal-Price et al.
PHARMACOLOGY & THERAPEUTICS (2017)
Quantitative weight of evidence to assess confidence in potential modes of action
Richard A. Becker et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2017)
Weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death
Carlie A. LaLone et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2017)
Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework
Iman Hassan et al.
TOXICOLOGICAL SCIENCES (2017)
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies
Zenggang Li et al.
NATURE COMMUNICATIONS (2017)
Adverse outcome pathways: a concise introduction for toxicologists
Mathieu Vinken et al.
ARCHIVES OF TOXICOLOGY (2017)
Systems Toxicology: Real World Applications and Opportunities
Thomas Hartung et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2017)
Adverse outcome pathways: From research to regulation scientific workshop report
Nicole C. Kleinstreuer et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)
A weight of evidence assessment approach for adverse outcome pathways
Zachary A. Collier et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)
Adverse Outcome Pathways-Organizing Toxicological Information to Improve Decision Making
Stephen W. Edwards et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes
Anna Bal-Price et al.
ARCHIVES OF TOXICOLOGY (2015)
Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy
Joanna S. Jaworska et al.
ARCHIVES OF TOXICOLOGY (2015)
Putative adverse outcome pathways relevant to neurotoxicity
Anna Bal-Price et al.
CRITICAL REVIEWS IN TOXICOLOGY (2015)
The potential of AOP networks for reproductive and developmental toxicity assay development
Dries Knapen et al.
REPRODUCTIVE TOXICOLOGY (2015)
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models
Luise Schultz et al.
TOXICOLOGY IN VITRO (2015)
Systems Toxicology: From Basic Research to Risk Assessment
Shana J. Sturla et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2014)
Adverse Outcome Pathway (AOP) Development I: Strategies and Principles
Daniel L. Villeneuve et al.
TOXICOLOGICAL SCIENCES (2014)
Adverse Outcome Pathway Development II: Best Practices
Daniel L. Villeneuve et al.
TOXICOLOGICAL SCIENCES (2014)
ADVERSE OUTCOME PATHWAYS: A CONCEPTUAL FRAMEWORK TO SUPPORT ECOTOXICOLOGY RESEARCH AND RISK ASSESSMENT
Gerald T. Ankley et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2010)
TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY
Daniel Krewski et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
Computing topological parameters of biological networks
Yassen Assenov et al.
BIOINFORMATICS (2008)
Protein adduct formation as a molecular mechanism in neurotoxicity
RM LoPachin et al.
TOXICOLOGICAL SCIENCES (2005)
Network biology:: Understanding the cell's functional organization
AL Barabási et al.
NATURE REVIEWS GENETICS (2004)
The changing view of acrylamide neurotoxicity
RM LoPachin
NEUROTOXICOLOGY (2004)