期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 361, 期 21, 页码 4914-4918出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201900813
关键词
Cyanation; Lewis acid; Phenols; N-Cyano-N-phenyl-p-toluenesulfonamide
资金
- National Natural Science Foundation of China [21702056, 21971059, 21605070]
- National Program for Thousand Young Talents of China
- Fundamental Research Funds for the Central Universities
Lewis acid-mediated cyanation of phenol derivatives with N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) has been developed. The reaction proceeded efficiently with high regioselectivity to produce aromatic nitriles in moderate to excellent yields, which provides a direct and practical access to valuable products.
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