相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome
Siamak MahmoudianDehkordi et al.
ALZHEIMERS & DEMENTIA (2019)
Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis
Francesca De Giorgio et al.
DISEASE MODELS & MECHANISMS (2019)
Comparative electrophysiological analysis of the bile acid-sensitive ion channel (BASIC) from different species suggests similar physiological functions
Pia Lenzig et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2019)
Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer's disease
Josef Marksteiner et al.
METABOLOMICS (2018)
Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats
Rita Soares et al.
MOLECULAR NEUROBIOLOGY (2018)
Intra- and Intercellular Quality Control Mechanisms of Mitochondria
Yoshimitsu Kiriyama et al.
CELLS (2018)
Tauroursodeoxycholic Acid Improves Motor Symptoms in a Mouse Model of Parkinson's Disease
Alexandra Isabel Rosa et al.
MOLECULAR NEUROBIOLOGY (2018)
Structure-Dependent Activity of Natural GABA(A) Receptor Modulators
Serhat Sezai Cicek
MOLECULES (2018)
Mechanism of parkin activation by PINK1
Christina Gladkova et al.
NATURE (2018)
INTRACELLULAR cAMP SENSOR EPAC: PHYSIOLOGY, PATHOPHYSIOLOGY, AND THERAPEUTICS DEVELOPMENT
William G. Robichaux et al.
PHYSIOLOGICAL REVIEWS (2018)
Role of Bile Acids in Metabolic Control
Antonio Molinaro et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2018)
A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease
Estela Area-Gomez et al.
CELL DEATH & DISEASE (2018)
Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5
Effendi Ibrahim et al.
SCIENTIFIC REPORTS (2018)
Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies
Katrin Juenemann et al.
SCIENTIFIC REPORTS (2018)
Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release
Shengnan Zhao et al.
Journal of Immunology Research (2018)
Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease
Simon M. Bell et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Phospholipid and Lipid Derivatives as Potential Neuroprotective Compounds
Seyed Khosrow Tayebati
MOLECULES (2018)
Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients
Tanja M. Sarenac et al.
FRONTIERS IN PHARMACOLOGY (2018)
Role and Cytotoxicity of Amylin and Protection of Pancreatic Islet β-Cells from Amylin Cytotoxicity
Yoshimitsu Kiriyama et al.
CELLS (2018)
Flux-Independent NMDAR Signaling: Molecular Mediators, Cellular Functions, and Complexities
Pavel Montes de Oca Balderas
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Overview of Bile Acids Signaling and Perspective on the Signal of Ursodeoxycholic Acid, the Most Hydrophilic Bile Acid, in the Heart
Noorul Izzati Hanafi et al.
BIOMOLECULES (2018)
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
Niamh M. C. Connolly et al.
CELL DEATH AND DIFFERENTIATION (2018)
Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease
Sara Moreira et al.
EXPERIMENTAL NEUROLOGY (2017)
Sphingosine 1-Phosphate (S1P) Signaling in Glioblastoma MultiformeA Systematic Review
Shailaja Mahajan-Thakur et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism
Preeti Pathak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials
Morten Hansen et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2017)
Hypothalamic Tuberomammillary Nucleus Neurons: Electrophysiological Diversity and Essential Role in Arousal Stability
Akie Fujita et al.
JOURNAL OF NEUROSCIENCE (2017)
The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition
Hui-Qiong He et al.
MOLECULES (2017)
Inactivation of the Tuberomammillary Nucleus by GABAA Receptor Agonist Promotes Slow Wave Sleep in Freely Moving Rats and Histamine-Treated Rats
Jun-Fan Xie et al.
NEUROCHEMICAL RESEARCH (2017)
MOLECULAR DETERMINANTS OF BK CHANNEL FUNCTIONAL DIVERSITY AND FUNCTIONING
Ramon Latorre et al.
PHYSIOLOGICAL REVIEWS (2017)
Unconjugated bile acids in rat brain: Analytical method based on LC/ESI-MS/MS with chemical derivatization and estimation of their origin by comparison to serum levels
Tatsuya Higashi et al.
STEROIDS (2017)
Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice
Matthew McMillin et al.
Frontiers in Cellular Neuroscience (2017)
Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3
Takahiro Suga et al.
PLOS ONE (2017)
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
Simona De Marino et al.
SCIENTIFIC REPORTS (2017)
Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease
Alexandra I. Rosa et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's Disease
Xiaobei Pan et al.
METABOLITES (2017)
Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases
Ju Gao et al.
ANTIOXIDANTS (2017)
Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis
A. E. Elia et al.
EUROPEAN JOURNAL OF NEUROLOGY (2016)
Sphingosine-1-Phosphate Receptors in the Central Nervous and Immune Systems
Luke M. Healy et al.
CURRENT DRUG TARGETS (2016)
Identification of functional farnesoid X receptors in brain neurons
Chao Huang et al.
FEBS LETTERS (2016)
Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives
Igor A. Schepetkin et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2016)
Activation of the Human Epithelial Sodium Channel (ENaC) by Bile Acids Involves the Degenerin Site
Alexandr V. Ilyaskin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet Cells to Promote Glucose Homeostasis
Divya P. Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The Brain Metabolome of Male Rats across the Lifespan
Xiaojiao Zheng et al.
SCIENTIFIC REPORTS (2016)
Bile acid: a potential inducer of colon cancer stem cells
Lulu Farhana et al.
STEM CELL RESEARCH & THERAPY (2016)
TGR5, Not Only a Metabolic Regulator
Cong Guo et al.
FRONTIERS IN PHYSIOLOGY (2016)
Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations
Noha F. Abdelkader et al.
MOLECULAR NEUROBIOLOGY (2016)
D-Amino Acids in the Nervous and Endocrine Systems
Yoshimitsu Kiriyama et al.
SCIENTIFICA (2016)
Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later
Allison M. Bond et al.
CELL STEM CELL (2015)
Regulation of neuronal communication by G protein-coupled receptors
Yunhong Huang et al.
FEBS LETTERS (2015)
The Function of Autophagy in Neurodegenerative Diseases
Yoshimitsu Kiriyama et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
Jin-Mi Heo et al.
MOLECULAR CELL (2015)
Suppression of the HPA Axis During Cholestasis Can Be Attributed to Hypothalamic Bile Acid Signaling
Matthew McMillin et al.
MOLECULAR ENDOCRINOLOGY (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
Huntington Disease Pathogenesis and Treatment
Praveen Dayalu et al.
NEUROLOGIC CLINICS (2015)
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson's Disease
Alicia M. Pickrell et al.
NEURON (2015)
THE ORGANIC ANION TRANSPORTER (OAT) FAMILY: A SYSTEMS BIOLOGY PERSPECTIVE
Sanjay K. Nigam et al.
PHYSIOLOGICAL REVIEWS (2015)
Structural basis of human γ-secretase assembly
Linfeng Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Amyotrophic lateral sclerosis: Current perspectives from basic research to the clinic
Renzo Mancuso et al.
PROGRESS IN NEUROBIOLOGY (2015)
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
Changtao Jiang et al.
NATURE COMMUNICATIONS (2015)
NMDA Receptor Function During Senescence: Implication on Cognitive Performance
Ashok Kumar
FRONTIERS IN NEUROSCIENCE (2015)
Thematic Review Series: Intestinal Lipid Metabolism: New Developments and Current Insights Intestinal transport and metabolism of bile acids
Paul A. Dawson et al.
JOURNAL OF LIPID RESEARCH (2015)
Glycoursodeoxycholic Acid Reduces Matrix Metalloproteinase-9 and Caspase-9 Activation in a Cellular Model of Superoxide Dismutase-1 Neurodegeneration
Ana Rita Vaz et al.
MOLECULAR NEUROBIOLOGY (2015)
International Union of Basic and Clinical Pharmacology. XCI. Structure, Function, and Pharmacology of Acid-Sensing Ion Channels and the Epithelial Na+ Channel
Stephan Kellenberger et al.
PHARMACOLOGICAL REVIEWS (2015)
Nuclear Receptors, RXR, and the Big Bang
Ronald M. Evans et al.
CELL (2014)
The bile acid-sensitive ion channel (BASIC), the ignored cousin of ASICs and ENaC
Dominik Wiemuth et al.
CHANNELS (2014)
Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms
Matthew Quinn et al.
DIGESTIVE AND LIVER DISEASE (2014)
The bile acid TGR5 membrane receptor: From basic research to clinical application
Henri Duboc et al.
DIGESTIVE AND LIVER DISEASE (2014)
Molecular mechanism of intramembrane proteolysis by γ-secretase
Taisuke Tomita
JOURNAL OF BIOCHEMISTRY (2014)
Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
Steven E. Kahn et al.
LANCET (2014)
The many faces of diabetes: a disease with increasing heterogeneity
Tiinamaija Tuomi et al.
LANCET (2014)
State of play in amyotrophic lateral sclerosis genetics
Alan E. Renton et al.
NATURE NEUROSCIENCE (2014)
Muscarinic acetylcholine receptors: novel opportunities for drug development
Andrew C. Kruse et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
Anatoliy I. Masyuk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)
Expression of bile acid receptor TGR5 in gastric adenocarcinoma
Weibiao Cao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)
Biological roles of cAMP: variations on a theme in the different kingdoms of life
Juana M. Gancedo
BIOLOGICAL REVIEWS (2013)
Pleiotropic Roles of Bile Acids in Metabolism
Thomas Q. de Aguiar Vallim et al.
CELL METABOLISM (2013)
Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
Sama I. Sayin et al.
CELL METABOLISM (2013)
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption
Guoxiang Xie et al.
FASEB JOURNAL (2013)
The profile of bile acids and their sulfate metabolites in human urine and serum
Sai Praneeth R. Bathena et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2013)
Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives
Hiroyuki Masuno et al.
JOURNAL OF LIPID RESEARCH (2013)
Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes
Yulin Wu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice
Adrian C. Lo et al.
NEUROBIOLOGY OF DISEASE (2013)
Glucocorticoid receptor signaling in health and disease
Mahita Kadmiel et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
Fei Li et al.
NATURE COMMUNICATIONS (2013)
Linking Metabolic Abnormalities to Apoptotic Pathways in Beta Cells in Type 2 Diabetes
Jibran Wali et al.
Cells (2013)
Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease
Terina N. Martinez et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Role of Epac in brain and heart
Anne-Coline Laurent et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes
Elaine Studer et al.
HEPATOLOGY (2012)
β-Subunit of the Ostα-Ostβ Organic Solute Transporter Is Required Not Only for Heterodimerization and Trafficking but Also for Function
Whitney V. Christian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Analysis of bioactive oxysterols in newborn mouse brain by LC/MS
Anna Meljon et al.
JOURNAL OF LIPID RESEARCH (2012)
TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice
Ana F. Nunes et al.
MOLECULAR NEUROBIOLOGY (2012)
Tauroursodeoxycholic Acid Prevents MPTP-Induced Dopaminergic Cell Death in a Mouse Model of Parkinson's Disease
M. Castro-Caldas et al.
MOLECULAR NEUROBIOLOGY (2012)
The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABAA receptors
S. R. Schubring et al.
NEUROSCIENCE LETTERS (2012)
Gender-Divergent Profile of Bile Acid Homeostasis during Aging of Mice
Zidong Donna Fu et al.
PLOS ONE (2012)
Waking Action of Ursodeoxycholic Acid (UDCA) Involves Histamine and GABAA Receptor Block
Yevgenij Yanovsky et al.
PLOS ONE (2012)
27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols
Robert J. Fakheri et al.
STEROIDS (2012)
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Anny-Claude Luissint et al.
FLUIDS AND BARRIERS OF THE CNS (2012)
Role of nuclear receptor SHP in metabolism and cancer
Yuxia Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Nuclear receptor PXR, transcriptional circuits and metabolic relevance
Chibueze A. Ihunnah et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Organic Anion-Transporting Polypeptide 1b2 (Oatp1b2) Is Important for the Hepatic Uptake of Unconjugated Bile Acids: Studies in Oatp1b2-Null Mice
Ivan L. Csanaky et al.
HEPATOLOGY (2011)
The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunit
Anna N. Bukiya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Alzheimer's Disease: The Challenge of the Second Century
David M. Holtzman et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene
Petr Pavek et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
Ju-Hyun Lee et al.
CELL (2010)
Safety, Tolerability, and Cerebrospinal Fluid Penetration of Ursodeoxycholic Acid in Patients With Amyotrophic Lateral Sclerosis
Gareth J. Parry et al.
CLINICAL NEUROPHARMACOLOGY (2010)
Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma
Jie Hong et al.
GUT (2010)
Genome-Wide Tissue-Specific Farnesoid X Receptor Binding in Mouse Liver and Intestine
Ann M. Thomas et al.
HEPATOLOGY (2010)
Bile salts of vertebrates: structural variation and possible evolutionary significance
Alan F. Hofmann et al.
JOURNAL OF LIPID RESEARCH (2010)
3-Nitropropionic Acid as a Tool to Study the Mechanisms Involved in Huntington's Disease: Past, Present and Future
Isaac Tunez et al.
MOLECULES (2010)
Expression and Signaling of Formyl-Peptide Receptors in the Brain
Fabio Cattaneo et al.
NEUROCHEMICAL RESEARCH (2010)
Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M2 Receptors in Neonatal Rat Cardiomyocytes
Siti H. Sheikh Abdul Kadir et al.
PLOS ONE (2010)
Occludin Phosphorylation in Regulation of Epithelial Tight Junctions
Radhakrishna Rao
MOLECULAR STRUCTURE AND FUNCTION OF THE TIGHT JUNCTION: FROM BASIC MECHANISMS TO CLINICAL MANIFESTATIONS (2009)
Fifty years of advances in bile acid synthesis and metabolism
David W. Russell
JOURNAL OF LIPID RESEARCH (2009)
Bile acids: regulation of synthesis
John Y. L. Chiang
JOURNAL OF LIPID RESEARCH (2009)
The Human G93A-Superoxide Dismutase-1 Mutation, Mitochondrial Glutathione and Apoptotic Cell Death
H. Muyderman et al.
NEUROCHEMICAL RESEARCH (2009)
Role of vitamin D receptor in the lithocholic acid- mediated CYP3A induction in vitro and in vivo
Tsutomu Matsubara et al.
DRUG METABOLISM AND DISPOSITION (2008)
Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTπ, at the blood-brain barrier
Bjoern Bauer et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2008)
Evolution of the bile salt nuclear receptor FXR in vertebrates
Erica J. Reschly et al.
JOURNAL OF LIPID RESEARCH (2008)
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
Hiroyuki Sato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Parkinson's disease: clinical features and diagnosis
J. Jankovic
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Targeting bile-acid signalling for metabolic diseases
Charles Thomas et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Epac: effectors and biological functions
Sara S. Roscioni et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
Cloning and functional expression of a new epithelial sodium channel δ subunit isoform differentially expressed in neurons of the human and monkey telencephalon
Teresa Giraldez et al.
JOURNAL OF NEUROCHEMISTRY (2007)
A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model
Francois-Pierre J. Martin et al.
MOLECULAR SYSTEMS BIOLOGY (2007)
Regional distribution of solute carrier mRNA expression along the human intestinal tract
Yvonne Meier et al.
DRUG METABOLISM AND DISPOSITION (2007)
Pregnane X receptor is a target of farnesoid X receptor
Diana Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder
Paul Abrams et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
OSTα-OSTβ:: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
N Ballatori et al.
HEPATOLOGY (2005)
Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M3 receptor-dependent
S Khurana et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2005)
Vitamin D receptor-dependent regulation of colon multidrug resistance-associated protein 3 gene expression by bile acids
TC McCarthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Crossing the barrier:: net flux of 27-hydroxycholesterol into the human brain
M Heverin et al.
JOURNAL OF LIPID RESEARCH (2005)
The identification of ligand features essential for PXR activation by pharmacophore modeling
D Schuster et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2005)
The heteromeric organic solute transporter α-β, ostα-ostβ, is an ileal basolateral bile acid transporter
PA Dawson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The interaction between bacteria and bile
M Begley et al.
FEMS MICROBIOLOGY REVIEWS (2005)
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription
TG Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain
N Mano et al.
JOURNAL OF LIPID RESEARCH (2004)
Bioconversion of 3β-hydroxy-5-cholenoic acid into chenodeoxycholic acid by rat brain enzyme systems
N Mano et al.
JOURNAL OF LIPID RESEARCH (2004)
Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1α -: Functional implications in hepatic cholesterol and glucose metabolism
S Bhalla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats
S Choudhuri et al.
DRUG METABOLISM AND DISPOSITION (2003)
Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover
EG Lund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Bile salt transporters: Molecular characterization, function, and regulation
M Trauner et al.
PHYSIOLOGICAL REVIEWS (2003)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of membrane-type receptor for bile acids (M-BAR)
T Maruyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
SA Kliewer et al.
ENDOCRINE REVIEWS (2002)
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic model of Huntington's disease
CD Keene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Vitamin D receptor as an intestinal bile acid sensor
M Makishima et al.
SCIENCE (2002)
LXRα is the dominant regulator of CYP7A1 transcription
S Gupta et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
PXR, CAR and drug metabolism
TM Willson et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants
X Chen et al.
BIOCHEMICAL PHARMACOLOGY (2002)
Regulation of multidrug resistance-associated protein 2 (ABCC2) by nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
HR Kast et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Functional modulation of the glucocorticoid receptor and suppression of NF-κB-dependent transcription by ursodeoxycholic acid
T Miura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
CD Keene et al.
EXPERIMENTAL NEUROLOGY (2001)
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
JL Staudinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice
S Alberti et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Reciprocal activation of Xenobiotic response genes by nuclear receptors SXR/PXR and CAR
W Xie et al.
GENES & DEVELOPMENT (2000)
Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors
X Chen et al.
INFLAMMATION RESEARCH (2000)
Selective activation of liver X receptor alpha by 6α-hydroxy bile acids and analogs
C Song et al.
STEROIDS (2000)
Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor
BA Laffitte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)