相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Epigenome modifiers and metabolic rewiring: New frontiers in therapeutics
Alessandra Ferrari et al.
PHARMACOLOGY & THERAPEUTICS (2019)
Epigenetic modulation of metabolism in glioblastoma
Zhen Dong et al.
SEMINARS IN CANCER BIOLOGY (2019)
Lactate: A Metabolic Driver in the Tumour Landscape
Luigi Ippolito et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
Control of the Antitumor Immune Response by Cancer Metabolism
Charlotte Domblides et al.
CELLS (2019)
Oncometabolites in cancer aggressiveness and tumour repopulation
Ilaria Dando et al.
BIOLOGICAL REVIEWS (2019)
HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy
Valentina Condelli et al.
CELLS (2019)
IDH3α regulates one-carbon metabolism in glioblastoma
Jasmine L. May et al.
SCIENCE ADVANCES (2019)
Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape
Gianmarco Rinaldi et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2018)
Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications
Niaz Mahmood et al.
ONCOTARGET (2018)
Metabolic Signaling to Epigenetic Alterations in Cancer
Jung-Ae Kim et al.
BIOMOLECULES & THERAPEUTICS (2018)
Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer
Xianmin Mu et al.
CELL CYCLE (2018)
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jingjing Chen et al.
NATURE GENETICS (2018)
Spatiotemporal Control of Acetyl-CoA Metabolism in Chromatin Regulation
Sharanya Sivanand et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width
Ziwei Dai et al.
NATURE COMMUNICATIONS (2018)
Cancer epigenetics: Moving forward
Angela Nebbioso et al.
PLOS GENETICS (2018)
TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor
Danilo Swann Matassa et al.
GENES (2018)
Targeting Tumor Metabolism: A New Challenge to improve immunotherapy
Soumaya Kouidhi et al.
FRONTIERS IN IMMUNOLOGY (2018)
Metabolic intermediates - Cellular messengers talking to chromatin modifiers
Anna Nieborak et al.
MOLECULAR METABOLISM (2018)
Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy
Subhankar Biswas et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2018)
Metabolic Signaling to the Nucleus in Cancer
Sydney L. Campbell et al.
MOLECULAR CELL (2018)
Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer
Subhamoy Dasgupta et al.
NATURE (2018)
Metabolic Switch in the Tumor Microenvironment Determines Immune Responses to Anti-cancer Therapy
Barbara Wegiel et al.
FRONTIERS IN ONCOLOGY (2018)
S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs
Concetta Paola Ilisso et al.
CANCER CELL INTERNATIONAL (2018)
Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
Vera Miranda-Goncalves et al.
FRONTIERS IN GENETICS (2018)
The role of enasidenib in the treatment of mutant IDH2 acute myeloid leukemia
Iman Abou Dalle et al.
THERAPEUTIC ADVANCES IN HEMATOLOGY (2018)
Metabolism and Transcription in Cancer: Merging Two Classic Tales
Natalia Martin-Martin et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
TRAP1: a viable therapeutic target for future cancer treatments?
Giacomo Lettini et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2017)
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
Xinjian Li et al.
MOLECULAR CELL (2017)
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination
Sharanya Sivanand et al.
MOLECULAR CELL (2017)
The impact of cellular metabolism on chromatin dynamics and epigenetics
Michael A. Reid et al.
NATURE CELL BIOLOGY (2017)
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
Andrew M. Intlekofer et al.
NATURE CHEMICAL BIOLOGY (2017)
Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
C. C. Wong et al.
ONCOGENE (2017)
Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α
W. Wan et al.
ONCOGENE (2017)
Metabolic origins of spatial organization in the tumor microenvironment
Carlos Carmona-Fontaine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Epigenetic plasticity and the hallmarks of cancer
William A. Flavahan et al.
SCIENCE (2017)
Serine and Functional Metabolites in Cancer
Alice C. Newman et al.
TRENDS IN CELL BIOLOGY (2017)
Mitochondria and Epigenetics Crosstalk in Homeostasis and Stress
Olli Matilainen et al.
TRENDS IN CELL BIOLOGY (2017)
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
Katharine Yen et al.
CANCER DISCOVERY (2017)
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
Andrea E. Calvert et al.
CELL REPORTS (2017)
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation
Vinay Bulusu et al.
CELL REPORTS (2017)
Metabolic Hallmarks of Tumor and immune Cells in the Tumor Microenvironment
Kathrin Renner et al.
FRONTIERS IN IMMUNOLOGY (2017)
Oncometabolites: A New Paradigm for Oncology, Metabolism, and the Clinical Laboratory
Rebecca R. J. Collins et al.
CLINICAL CHEMISTRY (2017)
Genome Regulation by Polycomb and Trithorax: 70 Years and Counting
Bernd Schuettengruber et al.
CELL (2017)
Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer
Thai Q. Tran et al.
CLINICAL CANCER RESEARCH (2017)
Deletion of Lactate Dehydrogenase-A in Myeloid Cells Triggers Antitumor Immunity
Pankaj Seth et al.
CANCER RESEARCH (2017)
Regulation of hypoxia responses by flavin adenine dinucleotide-dependent modulation of HIF-1α protein stability
Suk-Jin Yang et al.
EMBO JOURNAL (2017)
The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox
Loreta M. Rodrigues et al.
CANCER & METABOLISM (2017)
Understanding the Intersections between Metabolism and Cancer Biology
Matthew G. Vander Heiden et al.
CELL (2017)
S-Adenosylmethionine Affects ERK1/2 and Stat3 Pathways and Induces Apotosis in Osteosarcoma Cells
Concetta Paola Ilisso et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor
Shun Matsuda et al.
NUCLEIC ACIDS RESEARCH (2016)
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
D. S. Matassa et al.
CELL DEATH AND DIFFERENTIATION (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation
In-Young Hwang et al.
CELL METABOLISM (2016)
Oncometabolites: Unconventional triggers of oncogenic signalling cascades
Marco Sciacovelli et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Undercover: gene control by metabolites and metabolic enzymes
Jan A. van der Knaap et al.
GENES & DEVELOPMENT (2016)
The importance of serine metabolism in cancer
Katherine R. Mattaini et al.
JOURNAL OF CELL BIOLOGY (2016)
Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes
Jean-Pierre Etchegaray et al.
MOLECULAR CELL (2016)
Compartmentation of Metabolites in Regulating Epigenomes of Cancer
Zhiqiang Zhao et al.
MOLECULAR MEDICINE (2016)
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Marco Sciacovelli et al.
NATURE (2016)
Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation
Min Pan et al.
NATURE CELL BIOLOGY (2016)
The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V. Liberti et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Metabolic Enzymes Moonlighting in the Nucleus: Metabolic Regulation of Gene Transcription
Aristeidis E. Boukouris et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Epigenetic control of the tumor microenvironment
David L. Marks et al.
EPIGENOMICS (2016)
Regulation of HK2 expression through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma
Hyun Gyu Lee et al.
ONCOTARGET (2016)
Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions
Shu-Hai Lin et al.
SCIENTIFIC REPORTS (2016)
Oncometabolic Nuclear Reprogramming of Cancer Stemness
Javier A. Menendez et al.
STEM CELL REPORTS (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
Metabolic control of epigenetics in cancer
Adam Kinnaird et al.
NATURE REVIEWS CANCER (2016)
Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo
Nicholas Shukeir et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Zachary T. Schug et al.
CANCER CELL (2015)
Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
Arieh Moussaieff et al.
CELL METABOLISM (2015)
Hypoxia Induces Production of L-2-Hydroxyglutarate
Andrew M. Intlekofer et al.
CELL METABOLISM (2015)
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
Federico Pietrocola et al.
CELL METABOLISM (2015)
Targeting of cancer stem cells by inhibitors of DNA and histone methylation
Richard L. Momparler et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2015)
Reciprocal Modulation of Histone Deacetylase Inhibitors Sodium Butyrate and Trichostatin A on the Energy Metabolism of Breast Cancer Cells
Mariana Figueiredo Rodrigues et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Lysine-Specific Demethylase 2 Suppresses Lipid Influx and Metabolism in Hepatic Cells
Katsuya Nagaoka et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism
Shanshan Li et al.
MOLECULAR CELL (2015)
Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation
Yuhui Jiang et al.
NATURE CELL BIOLOGY (2015)
Epithelial-mesenchymal transition in human cancer: Comprehensive reprogramming of metabolism, epigenetics, and differentiation
Linna Li et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells
Luyuan Li et al.
PLOS ONE (2015)
Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression
David Kozono et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Mitochondrial Proteins Moonlighting in the Nucleus
Richard M. Monaghan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Glycolytic metabolism influences global chromatin structure
Xue-Song Liu et al.
ONCOTARGET (2015)
5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits
Corti Denise et al.
ONCOTARGET (2015)
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey et al.
NATURE (2015)
The multifaceted functions of sirtuins in cancer
Angeliki Chalkiadaki et al.
NATURE REVIEWS CANCER (2015)
Critical protein GAPDH and its regulatory mechanisms in cancer cells
Jin-Ying Zhang et al.
CANCER BIOLOGY & MEDICINE (2015)
Nuclear lactate dehydrogenase modulates histone modification in human hepatocytes
Zachary Castonguay et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
Damya Laoui et al.
CANCER RESEARCH (2014)
A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
Gopinath Sutendra et al.
CELL (2014)
Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation
Joyce V. Lee et al.
CELL METABOLISM (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism
Hung-Jung Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Serine and glycine metabolism in cancer
Ivano Amelio et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect
Paula Lopez-Serra et al.
NATURE COMMUNICATIONS (2014)
A High-Throughput Fluorimetric Assay for 2-Hydroxyglutarate Identifies Zaprinast as a Glutaminase Inhibitor
Adnan Elhammali et al.
CANCER DISCOVERY (2014)
Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers
Shruti Desai et al.
ONCOTARGET (2014)
Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth
Jason Chesney et al.
ONCOTARGET (2014)
Epigenetic therapy of acute myeloid leukemia using 5-aza-2′-deoxycytidine (decitabine) in combination with inhibitors of histone methylation and deacetylation
Richard L. Momparler et al.
CLINICAL EPIGENETICS (2014)
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
Surendra K. Shukla et al.
CANCER & METABOLISM (2014)
The histone LSD1 demethylase in stemness and cancer transcription programs
Stefano Amente et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2013)
Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer
Agnieszka A. Rawluszko et al.
BMC CANCER (2013)
Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
Chenfang Dong et al.
CANCER CELL (2013)
DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
Xavier Tekpli et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
The histone deacetylase SIRT2 stabilizes Myc oncoproteins
P. Y. Liu et al.
CELL DEATH AND DIFFERENTIATION (2013)
The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
Marco Sciacovelli et al.
CELL METABOLISM (2013)
How are mammalian methionine adenosyltransferases regulated in the liver? A focus on redox stress
Maria A. Pajares et al.
FEBS LETTERS (2013)
Methionine Adenosyltransferase II-dependent Histone H3K9 Methylation at the COX-2 Gene Locus
Yohei Kera et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Histone Acetylation Regulates Intracellular pH
Matthew A. McBrian et al.
MOLECULAR CELL (2013)
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
Sakari Vanharanta et al.
NATURE MEDICINE (2013)
Comparative study of IDH1 mutations in gliomas by immunohistochemistry and DNA sequencing
Shipra Agarwal et al.
NEURO-ONCOLOGY (2013)
Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation
Dongning Pan et al.
PLOS ONE (2013)
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
Tadahiro Shimazu et al.
SCIENCE (2013)
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft
Alexandra Borodovsky et al.
ONCOTARGET (2013)
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
Sevin Turcan et al.
ONCOTARGET (2013)
Serine, glycine and one-carbon units: cancer metabolism in full circle
Jason W. Locasale
NATURE REVIEWS CANCER (2013)
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
Weiwei Yang et al.
CELL (2012)
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
Carlos Sebastian et al.
CELL (2012)
Connecting Threads: Epigenetics and Metabolism
Sayako Katada et al.
CELL (2012)
Ketone body utilization drives tumor growth and metastasis
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2012)
Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype
Natalie E. Simpson et al.
EPIGENETICS (2012)
S-Adenosylmethionine Inhibits the Growth of Cancer Cells by Reversing the Hypomethylation Status of c-myc and H-ras in Human Gastric Cancer and Colon Cancer
Jin Luo et al.
International Journal of Biological Sciences (2012)
Flavin-Dependent Enzymes in Cancer Prevention
Danuta Wojcieszynska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation
William C. Hallows et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation
Dallas R. Donohoe et al.
MOLECULAR CELL (2012)
Reductive carboxylation supports growth in tumour cells with defective mitochondria
Andrew R. Mullen et al.
NATURE (2012)
Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression
Tom Latham et al.
NUCLEIC ACIDS RESEARCH (2012)
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
Weibo Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Cancer Cell Metabolism: One Hallmark, Many Faces
Jason R. Cantor et al.
CANCER DISCOVERY (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Methionine Adenosyltransferase II Serves as a Transcriptional Corepressor of Maf Oncoprotein
Yasutake Katoh et al.
MOLECULAR CELL (2011)
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
Weiwei Yang et al.
NATURE (2011)
Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme
Amparo Wolf et al.
NEUROBIOLOGY OF DISEASE (2011)
Aberrant Promoter CpG Methylation Is a Mechanism for Impaired PHD3 Expression in a Diverse Set of Malignant Cells
Trenton L. Place et al.
PLOS ONE (2011)
Reduced Expression of Fumarate Hydratase in Clear Cell Renal Cancer Mediates HIF-2α Accumulation and Promotes Migration and Invasion
Sunil Sudarshan et al.
PLOS ONE (2011)
Energy Metabolism in H460 Lung Cancer Cells: Effects of Histone Deacetylase Inhibitors
Nivea Dias Amoedo et al.
PLOS ONE (2011)
Promoter Hypermethylation Mediated Downregulation of FBP1 in Human Hepatocellular Carcinoma and Colon Cancer
Mingquan Chen et al.
PLOS ONE (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Ketones and lactate fuel tumor growth and metastasis Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli et al.
CELL CYCLE (2010)
Structural studies on human 2-oxoglutarate dependent oxygenases
Michael A. McDonough et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation
Padma Madiraju et al.
Epigenetics (2010)
GAPDH mediates nitrosylation of nuclear proteins
Michael D. Kornberg et al.
NATURE CELL BIOLOGY (2010)
Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation
Gema Alcarraz-Vizan et al.
METABOLOMICS (2010)
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells
Warren Fiskus et al.
BLOOD (2009)
VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors
A. M. Schmitt et al.
ENDOCRINE-RELATED CANCER (2009)
Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution
Edel Reytor et al.
FASEB JOURNAL (2009)
Ketone bodies inhibit the viability of human neuroblastoma cells
Robert Skinner et al.
JOURNAL OF PEDIATRIC SURGERY (2009)
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
Tina Branscombe Miranda et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Glucose Metabolism as a Target of Histone Deacetylase Inhibitors
Suzanne E. Wardell et al.
MOLECULAR ENDOCRINOLOGY (2009)
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
Kathryn E. Wellen et al.
SCIENCE (2009)
NAD+/ NADH and NADP+/NADPH in cellular functions and cell death:: Regulation and biological consequences
Weihai Ying
ANTIOXIDANTS & REDOX SIGNALING (2008)
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death
Vivian Egler et al.
CLINICAL CANCER RESEARCH (2008)
Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)
Mary M. Robinson et al.
BIOCHEMICAL JOURNAL (2007)
Nucleocytosolic acetyl-coenzyme A synthetase is required for histone acetylation and global transcription
Hidekazu Takahashi et al.
MOLECULAR CELL (2006)
PTEN promoter methylation in sporadic thyroid carcinomas
F Alvarez-Nunez et al.
THYROID (2006)
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
MR Hara et al.
NATURE CELL BIOLOGY (2005)
Promoter methylation of the PTEN gene is a common molecular change in breast cancer
JM García et al.
GENES CHROMOSOMES & CANCER (2004)
Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1α activation
O Minchenko et al.
FEBS LETTERS (2004)
Glucose metabolism in cancer - Evidence that demethylation events play a role in activating type II hexokinase gene expression
A Goel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The key role of anaplerosis and cataplerosis for citric acid cycle function
OE Owen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Promoter methylation and silencing of PTEN in gastric carcinoma
YH Kang et al.
LABORATORY INVESTIGATION (2002)
Cytokines and immune response in the tumor microenvironment
S Mocellin et al.
JOURNAL OF IMMUNOTHERAPY (2001)
5′-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer
J Trojan et al.
GUT (2000)
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
M Esteller et al.
ONCOGENE (2000)
分享论文
