相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies
Maria Jimenez-Sanchez et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Caspase-2 and tau-a toxic partnership?
Carol M. Troy et al.
NATURE MEDICINE (2016)
Caspase-2 cleavage of tau reversibly impairs memory
Xiaohui Zhao et al.
NATURE MEDICINE (2016)
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
Tara E. Tracy et al.
NEURON (2016)
The role of tau in the pathological process and clinical expression of Huntington's disease
Romina Vuono et al.
BRAIN (2015)
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
Sang-Won Min et al.
NATURE MEDICINE (2015)
Mutant huntingtin alters Tau phosphorylation and subcellular distribution
David Blum et al.
HUMAN MOLECULAR GENETICS (2015)
Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease
Maud Gratuze et al.
HUMAN MOLECULAR GENETICS (2015)
Huntington's disease is a four-repeat tauopathy with tau nuclear rods
Marta Fernandez-Nogales et al.
NATURE MEDICINE (2014)
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
Zhentao Zhang et al.
NATURE MEDICINE (2014)
The Co-Occurrence of Alzheimer's Disease and Huntington's Disease: A Neuropathological Study of 15 Elderly Huntington's Disease Subjects
Marie Y. Davis et al.
JOURNAL OF HUNTINGTONS DISEASE (2014)
Exploiting differences in caspase-2 and-3 S2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors
Michel C. Maillard et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Grape Seed Polyphenolic Extract Specifically Decreases A beta*56 in the Brains of Tg2576 Mice
Peng Liu et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease
Jeffrey B. Carroll et al.
MOLECULAR NEURODEGENERATION (2011)
Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models
Melissa J. Leyva et al.
CHEMISTRY & BIOLOGY (2010)
Association of Corticobasal Degeneration and Huntington's Disease: Can Tau Aggregates Protect Huntingtin Toxicity?
Dominique Caparros-Lefebvre et al.
MOVEMENT DISORDERS (2009)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
Rona K. Graham et al.
CELL (2006)
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease
E Hermel et al.
CELL DEATH AND DIFFERENTIATION (2004)
A cell-based screen for drugs to treat Huntington's disease
CT Aiken et al.
NEUROBIOLOGY OF DISEASE (2004)
The biochemical mechanism of caspase-2 activation
BC Baliga et al.
CELL DEATH AND DIFFERENTIATION (2004)
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
YJ Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Juvenile onset Huntington's disease - Clinical and research perspectives
MA Nance et al.
MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS (2001)
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
CL Wellington et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)