期刊
CHEMISTRYSELECT
卷 4, 期 22, 页码 6697-6701出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.201901143
关键词
Double reductive cyclization; Microwave chemistry; Multicomponent reactions; 2-Oxothiazolidine dicarboxylate (2-OTDC); Regioselectivity
资金
- CSIR, New Delhi
A regioselective synthesis of 2-oxothiazolidine dicarboxylate (OTDC) under microwave irradiations is reported. Methoxylation, demethylation and double reductive cyclization occurs in single step by three component one pot reaction under microwave irradiations. The microwave irradiations, planar arrangement of intermediate imino(sp2)-thio-maleate and in situ demethylation considered as driving forces for regioselective cyclization.
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