4.7 Review

Current limitations and future opportunities for prediction of DILI from in vitro

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling

Isoude A. Kuijper et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)

Review Biotechnology & Applied Microbiology

Engineered Liver Platforms for Different Phases of Drug Development

Brenton R. Ware et al.

TRENDS IN BIOTECHNOLOGY (2017)

Article Biochemistry & Molecular Biology

WITHDRAWN-a resource for withdrawn and discontinued drugs

Vishal B. Siramshetty et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Chemistry, Medicinal

Reactive Metabolites: Current and Emerging Risk and Hazard Assessments

Richard A. Thompson et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2016)

Article Chemistry, Medicinal

Computational Models for Human and Animal Hepatotoxicity with a Global Application Scope

Denis Mulliner et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2016)

Article Medicine, Research & Experimental

Biology-Inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing

Uwe Marx et al.

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2016)

Review Biochemistry & Molecular Biology

Development of novel tools for the in vitro investigation of drug-induced liver injury

Jian Jiang et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2015)

Article Toxicology

Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

Natalie Mesens et al.

JOURNAL OF APPLIED TOXICOLOGY (2015)

Review Gastroenterology & Hepatology

Drug-induced liver injury: Interactions between drug properties and host factors

Minjun Chen et al.

JOURNAL OF HEPATOLOGY (2015)

Review Pharmacology & Pharmacy

The application of 3D cell models to support drug safety assessment: Opportunities & challenges

Adrian Roth et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Review Gastroenterology & Hepatology

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

Naga P. Chalasani et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2014)

Article Medicine, Research & Experimental

Toward predictive models for drug-induced liver injury in humans: are we there yet?

Minjun Chen et al.

BIOMARKERS IN MEDICINE (2014)

Review Pharmacology & Pharmacy

Zebrafish as model organisms for studying drug-induced liver injury

A. D. Bastiaan Vliegenthart et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)

Review Biochemistry & Molecular Biology

Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients

Mitchell R. McGill et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)

Review Biochemistry & Molecular Biology

Drug-induced liver injury: what was new in 2013?

Walid M. Chalhoub et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)

Review Medicine, General & Internal

Drug-Induced Liver Injury

Michael D. Leise et al.

MAYO CLINIC PROCEEDINGS (2014)

Editorial Material Gastroenterology & Hepatology

Predicting idiosyncratic drug-induced liver injury - some recent advances

Minjun Chen et al.

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2014)

Article Pharmacology & Pharmacy

The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity

Brandy Garzel et al.

DRUG METABOLISM AND DISPOSITION (2014)

Article Toxicology

Multi-cell type human liver microtissues for hepatotoxicity testing

S. Messner et al.

ARCHIVES OF TOXICOLOGY (2013)

Article Gastroenterology & Hepatology

Mechanisms of Drug-induced Liver Injury

Liyun Yuan et al.

CLINICS IN LIVER DISEASE (2013)

Editorial Material Gastroenterology & Hepatology

Avoiding Idiosyncratic DILI: Two Is Better Than One

Neil Kaplowitz

HEPATOLOGY (2013)

Article Pharmacology & Pharmacy

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

Radina Kostadinova et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)

Article Chemistry, Medicinal

Preclinical Strategy to Reduce Clinical Hepatotoxicity Using in Vitro Bioactivation Data for >200 Compounds

Melanie Z. Sakatis et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2012)

Article Chemistry, Medicinal

In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs

Richard A. Thompson et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2012)

Article Cardiac & Cardiovascular Systems

Ambrisentan

James E. Frampton

AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS (2011)

Review Pharmacology & Pharmacy

FDA-approved drug labeling for the study of drug-induced liver injury

Minjun Chen et al.

DRUG DISCOVERY TODAY (2011)

Article Biochemistry & Molecular Biology

Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?

Steven J. R. Meex et al.

JOURNAL OF LIPID RESEARCH (2011)

Article Pharmacology & Pharmacy

Intrinsic versus Idiosyncratic Drug-Induced Hepatotoxicity-Two Villains or One?

Robert A. Roth et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Toxicology

Cellular imaging predictions of clinical drug-induced liver injury

Jinghai J. Xu et al.

TOXICOLOGICAL SCIENCES (2008)

Review Pharmacology & Pharmacy

Mitochondrial abnonnalities - A link to idiosyncratic drug hepatotoxicity?

Urs A. Boelsterli et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)

Article Medicine, Legal

Concordance of the toxicity of pharmaceuticals in humans and in animals

H Olson et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2000)