期刊
INTERNATIONAL OPHTHALMOLOGY
卷 39, 期 12, 页码 2923-2928出版社
SPRINGER
DOI: 10.1007/s10792-019-01142-4
关键词
Herpes simplex; Herpetic keratitis; Anterior segment optical coherence tomography
PurposeTo describe the anterior segment AS-OCT findings of herpetic simplex keratitis.MethodsForty-two eyes of 42 patients with proven herpetic keratitis of varying severity were included in this prospective, observational, non-comparative case series study. All subjects underwent ophthalmologic examination and AS-OCT imaging.ResultsTwenty-five of the 42 eyes (59.5%) had sub-epithelial infiltrates. In 11 of these cases, the overlying epithelium appeared intact, but in 14 cases, hydropic changes, heaping, and defects were observed. Seventeen eyes (40.5%) showed stromal involvement: six cases with scar at presentation and one case associated with uveitis. Stromal infiltrates were also seen, in ten cases, as a diffuse or local lentiform or spindle-shaped hyper-reflective area in the stroma.ConclusionHerpetic keratouveitis has characteristic features on AS-OCT images. This study demonstrates that herpetic keratitis also has characteristic AS-OCT features, including sub-epithelial infiltration and specific stromal hyper-reflective patterns. These features are not unique to herpetic keratitis, but AS-OCT imaging may provide useful supplementary information for diagnosing and monitoring herpetic keratitis.
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