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Ryan H. Gumpper et al.
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Christopher C. Stobart et al.
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Dusan Kunec et al.
CELL REPORTS (2016)
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Eleanor Gaunt et al.
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Generation of Live Attenuated Influenza Virus by Using Codon Usage Bias
Rebecca L. Y. Fan et al.
JOURNAL OF VIROLOGY (2015)
Codon Bias as a Means to Fine-Tune Gene Expression
Tessa E. F. Quax et al.
MOLECULAR CELL (2015)
Synthetic Biology for Therapeutic Applications
Zhanar Abil et al.
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Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?
J. J. Bull
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Large-Scale Nucleotide Optimization of Simian Immunodeficiency Virus Reduces Its Capacity To Stimulate Type I Interferon In Vitro
Nicolas Vabret et al.
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Influenza A Virus Attenuation by Codon Deoptimization of the NS Gene for Vaccine Development
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The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication
Nicky J. Atkinson et al.
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Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization
Cyril Le Nouen et al.
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Computer-aided codon-pairs deoptimization of the major envelope GP5 gene attenuates porcine reproductive and respiratory syndrome virus
Yan-Yan Ni et al.
VIROLOGY (2014)
Refining the Balance of Attenuation and Immunogenicity of Respiratory Syncytial Virus by Targeted Codon Deoptimization of Virulence Genes
Jia Meng et al.
MBIO (2014)
RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies
F. Tulloch et al.
ELIFE (2014)
Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice
Chen Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Random Codon Re-encoding Induces Stable Reduction of Replicative Fitness of Chikungunya Virus in Primate and Mosquito Cells
Antoine Nougairede et al.
PLOS PATHOGENS (2013)
Slow Fitness Recovery in a Codon-Modified Viral Genome
J. J. Bull et al.
MOLECULAR BIOLOGY AND EVOLUTION (2012)
Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development
Natalia Goni et al.
VIROLOGY JOURNAL (2012)
Synonymous but not the same: the causes and consequences of codon bias
Joshua B. Plotkin et al.
NATURE REVIEWS GENETICS (2011)
Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus
Emily H. M. Wong et al.
BMC EVOLUTIONARY BIOLOGY (2010)
Live attenuated influenza virus vaccines by computer-aided rational design
Steffen Mueller et al.
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Rationalizing the development of live attenuated virus vaccines
Adam S. Lauring et al.
NATURE BIOTECHNOLOGY (2010)
Translation efficiency is determined by both codon bias and folding energy
Tamir Tuller et al.
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Fine-Tuning Translation Kinetics Selection as the Driving Force of Codon Usage Bias in the Hepatitis A Virus Capsid
Lluis Aragones et al.
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Selection on Codon Bias
Ruth Hershberg et al.
ANNUAL REVIEW OF GENETICS (2008)
Virus attenuation by genome-scale changes in codon pair bias
J. Robert Coleman et al.
SCIENCE (2008)
Tissue-specific differences in human transfer RNA expression
Kimberly A. Dittmar et al.
PLOS GENETICS (2006)
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity
Steffen Mueller et al.
JOURNAL OF VIROLOGY (2006)
Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region
CC Burns et al.
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A periodic pattern of mRNA secondary structure created by the genetic code
Svetlana A. Shabalina et al.
NUCLEIC ACIDS RESEARCH (2006)
tRNA properties help shape codon pair preferences in open reading frames
JR Buchan et al.
NUCLEIC ACIDS RESEARCH (2006)
CpG RNA:: Identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes
T Sugiyama et al.
JOURNAL OF IMMUNOLOGY (2005)
Codon bias and heterologous protein expression
C Gustafsson et al.
TRENDS IN BIOTECHNOLOGY (2004)
The extent of codon usage bias in human RNA viruses and its evolutionary origin
GM Jenkins et al.
VIRUS RESEARCH (2003)
Pushing the limits of the scanning mechanism for initiation of translation
M Kozak
GENE (2002)
Chemical synthesis of poliovirus cDNA: Generation of infectious virus in the absence of natural template
J Cello et al.
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