期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 39, 期 10, 页码 1433-1440出版社
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-016-0800-2
关键词
Chrysin; Glycosylation; Derivative; Antitumor activity; Antioxidant activity; Antimicrobial activity
资金
- National Spark Key Program of China [2015GA610001]
- Foundation of Tianjin University of Science and Technology [20120106]
- International Science and Technology Cooperation Program of China [2013DFA31160]
- Foundation of Tianjin Educational Committee [20090604]
Chrysin-beta-d-galactopyranoside was efficiently synthesized, evaluated for its inhibitory activities against H22 cell lines compared with chrysin, the scavenging of hydroxyl radical, DPPH radical and superoxide anion, inhibitory effect against bacteria and fungi. The structures of all compounds were fully characterized by spectroscopic data (NMR, MS). The anti-tumor, antioxidant and antimicrobial activities of chrysin-beta-d-galactopyranoside were proved to be enhanced significantly compared with chrysin.
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