期刊
ALLERGOLOGY INTERNATIONAL
卷 68, 期 4, 页码 413-419出版社
JAPANESE SOC ALLERGOLOGY
DOI: 10.1016/j.alit.2019.05.006
关键词
Acute eosinophilic pneumonia; Chronic eosinophilic pneumonia; Pulmonary function tests; Relapse; Smoking habit
资金
- Japan Society for the Promotion of Science and scholarship grant for research in basic medical science and medical care [19K17632]
- Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care [18KI050]
- Grants-in-Aid for Scientific Research [19K17632] Funding Source: KAKEN
Eosinophilic pneumonia (EP) is a rare disorder, comprising several heterogeneous diseases. Two major types of EP are acute eosinophilic pneumonia (AEP) and chronic eosinophilic pneumonia (CEP), both of which are characterized by marked accumulation of eosinophils in lung tissues and/or BAL fluid. AEP and CEP share some similarities in terms of pathophysiology, radiological findings, and treatment response to corticosteroids. However, they distinctly differ in etiology, clinical manifestations, and the nature of disease course. Especially, although AEP and CEP respond well to corticosteroids, relapse frequently occurs in patients with CEP, but rarely in those with AEP. Although CEP occasionally persists and becomes corticosteroid dependent, most patients with AEP completely recover. This article reviews previous studies and discusses the etiology, clinical manifestations, and treatment of AEP and CEP. Copyright (C) 2019, Japanese Society of Allergology. Production and hosting by Elsevier B.V.
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