期刊
ASIAN JOURNAL OF ORGANIC CHEMISTRY
卷 8, 期 8, 页码 1472-1478出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201900382
关键词
copper-catalyzed; organosulfone; sulfonylacetonitrile; one-pot; N-heterocycle
资金
- Natural Science Foundation of Shandong Province [ZR2016JL012]
- National Natural Science Foundation of China [21302110]
A simple and practical copper-catalyzed one pot synthesis of C-4 sulfonated isoquinolin-1(2H)-ones has been developed. To the best of our knowledge, this is the first example for the synthesis of sulfone-containing heterocycles through transition-metal-catalyzed Ullmann-type coupling reactions using sulfonylacetonitriles as the sulfonylating agents.
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