期刊
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
卷 47, 期 1, 页码 2800-2809出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/21691401.2019.1638791
关键词
Diagnosis; microRNA; prognosis; treatment; triple-negative breast cancer
资金
- Innovation platform Open Foundation of education department of Hunan province [16K079, 17K082]
- University of South China Innovation Foundation For Postgraduate
Triple-negative breast cancer (TNBC) is a distinct subtype of breast cancer characterized by high recurrence rates and poor prognosis compared to other breast cancers. MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of various post-transcriptional gene and silence a broad set of target genes. Many recent studies have demonstrated that miRNAs play an important role in the initiation, promotion, malignant conversion, progression, and metastasis of TNBC. Therefore, the aim of this review is to focus on recent advancements of microRNAs-based potential applications in diagnosis, treatment and prognosis of triple-negative breast cancer.
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