相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)
Seung-Hyeon Seok et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
In vitro toxicity and in silico docking analysis of two novel selective AH-receptor modulators
Selma Mahiout et al.
TOXICOLOGY IN VITRO (2018)
Ligand-induced perturbation of the HIF-2α: ARNT dimer dynamics
Stefano Motta et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist
Samantha C. Faber et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling
Yating Cheng et al.
TOXICOLOGICAL SCIENCES (2017)
Structural modeling of the AhR: ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization
Dario Corrada et al.
MOLECULAR BIOSYSTEMS (2017)
Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats
Selma Mahiout et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)
Structural characterization of mammalian bHLH-PAS transcription factors
Dalei Wu et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation
Dario Corrada et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2
Thomas H. Scheuerrnann et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Structural integration in hypoxia-inducible factors
Dalei Wu et al.
NATURE (2015)
The Aryl Hydrocarbon Receptor in Barrier Organ Physiology, Immunology, and Toxicology
Charlotte Esser et al.
PHARMACOLOGICAL REVIEWS (2015)
The Aryl Hydrocarbon Receptor: Multitasking in the Immune System
Brigitta Stockinger et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
Exploring the role of receptor flexibility in structure-based drug discovery
Ferran Feixas et al.
BIOPHYSICAL CHEMISTRY (2014)
Ligand Binding and Functional Selectivity of L-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR)
Roberto Nuti et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis
Anatoly A. Soshilov et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
Alban Bessede et al.
NATURE (2014)
AhR sensing of bacterial pigments regulates antibacterial defence
Pedro Moura-Alves et al.
NATURE (2014)
Aryl hydrocarbon receptor ligands in cancer: friend and foe
Iain A. Murray et al.
NATURE REVIEWS CANCER (2014)
Comparative Analysis of Homology Models of the Ah Receptor Ligand Binding Domain: Verification of Structure-Function Predictions by Site-Directed Mutagenesis of a Nonfunctional Receptor
Domenico Fraccalvieri et al.
BIOCHEMISTRY (2013)
Role of aryl hydrocarbon receptor in cancer
Shaolong Feng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2013)
The AhR twist: ligand-dependent AhR signaling and pharmaco-toxicological implications
Erwan Guyot et al.
DRUG DISCOVERY TODAY (2013)
Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
Jamie L. Rogers et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
Thomas H. Scheuermann et al.
NATURE CHEMICAL BIOLOGY (2013)
An overview of the Amber biomolecular simulation package
Romelia Salomon-Ferrer et al.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2013)
The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression
Timothy V. Beischlag et al.
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2012)
AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish
Britton C. Goodale et al.
PLOS ONE (2012)
Identification of the Ah-Receptor Structural Determinants for Ligand Preferences
Yongna Xing et al.
TOXICOLOGICAL SCIENCES (2012)
New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability
Ilaria Motto et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Predicting the Accuracy of Protein-Ligand Docking on Homology Models
Annalisa Bordogna et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
The VSGB 2.0 model: A next generation energy model for high resolution protein structure modeling
Jianing Li et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor
Michael S. Denison et al.
TOXICOLOGICAL SCIENCES (2011)
Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution
Jeremy R. Greenwood et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2010)
An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
Francisco J. Quintana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Detection of the TCDD Binding-Fingerprint within the Ah Receptor Ligand Binding Domain by Structurally Driven Mutagenesis and Functional Analysis
Alessandro Pandini et al.
BIOCHEMISTRY (2009)
Molecular Docking Screens Using Comparative Models of Proteins
Hao Fan et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)
An Overview of the Effects of Dioxins and Dioxin-Like Compounds on Vertebrates, as Documented in Human and Ecological Epidemiology
SALLY S. WHITE et al.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS (2009)
Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands
William H. Bisson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B
Jason Key et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
Thomas H. Scheuermann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure and Signaling Mechanism of Per-ARNT-Sim Domains
Andreas Moeglich et al.
STRUCTURE (2009)
The search for endogenous activators of the aryl hydrocarbon receptor
Linh P. Nguyen et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Flexible ligand docking to multiple receptor conformations: a practical alternative
Maxim Totrov et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2008)
Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor
Anatoly Soshilov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins
Markus Wiederstein et al.
NUCLEIC ACIDS RESEARCH (2007)
Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis
Alessandro Pandini et al.
BIOCHEMISTRY (2007)
Statistical potential for assessment and prediction of protein structures
Min-Yi Shen et al.
PROTEIN SCIENCE (2006)
Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
Richard A. Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues
Joe Dundas et al.
NUCLEIC ACIDS RESEARCH (2006)
MUSCLE: multiple sequence alignment with high accuracy and high throughput
RC Edgar
NUCLEIC ACIDS RESEARCH (2004)
The mammalian basic helix-loop-helix/PAS family of transcriptional regulators
RJ Kewley et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Exploring protein native states and large-scale conformational changes with a modified generalized born model
A Onufriev et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Information decay in molecular docking screens against holo, apo, and modeled conformations of enzymes
SL McGovern et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models
PA Kollman et al.
ACCOUNTS OF CHEMICAL RESEARCH (2000)
Modeling of loops in protein structures
A Fiser et al.
PROTEIN SCIENCE (2000)
分享论文
