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注意:仅列出部分参考文献,下载原文获取全部文献信息。The Metabolomic Bioenergetic Signature of Opα1- Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency
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A Plasma Metabolomic Signature Involving Purine Metabolism in Human Optic Atrophy 1 (OPA1)-Related Disorders
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OPA1 haploinsufficiency induces a BNIP3-dependent decrease in mitophagy in neurons: relevance to Dominant Optic Atrophy
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JOURNAL OF NEUROCHEMISTRY (2017)
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
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Patrick Yu-Wai-Man et al.
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Juan Manuel Chao de la Barca et al.
BRAIN (2016)
Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
A. M. Bertholet et al.
NEUROBIOLOGY OF DISEASE (2016)
OPA1-related disorders: Diversity of clinical expression, modes of inheritance and pathophysiology
Juan Manuel Chao de la Barca et al.
NEUROBIOLOGY OF DISEASE (2016)
Loss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesis
Aurelie M. C. Millet et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
Kivanc Birsoy et al.
CELL (2015)
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Lucas B. Sullivan et al.
CELL (2015)
Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics
Angelika S. Rambold et al.
DEVELOPMENTAL CELL (2015)
Improved Locus-Specific Database for OPA1 Mutations Allows Inclusion of Advanced Clinical Data
Marc Ferre et al.
HUMAN MUTATION (2015)
OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand
David A. Patten et al.
EMBO JOURNAL (2014)
OPA1 loss of function affects in vitro neuronal maturation
Ambre M. Bertholet et al.
BRAIN (2013)
Membrane lipid unsaturation as physiological adaptation to animal longevity
Alba Naudi et al.
FRONTIERS IN PHYSIOLOGY (2013)
The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse
Emmanuelle Sarzi et al.
BRAIN (2012)
Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity
Pete A. Williams et al.
BRAIN (2012)
The Front-end Desaturase: Structure, Function, Evolution and Biotechnological Use
Dauenpen Meesapyodsuk et al.
LIPIDS (2012)
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis
Guillaume Pidoux et al.
EMBO JOURNAL (2011)
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution
Ghizlane Elachouri et al.
GENOME RESEARCH (2011)
A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
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CELL DEATH & DISEASE (2011)
Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy
Pete A. Williams et al.
BRAIN (2010)
Characterization of Ca2+ Signalling in Postnatal Mouse Retinal Ganglion Cells: Involvement of OPA1 in Ca2+ Clearance
Govindan Dayanithi et al.
OPHTHALMIC GENETICS (2010)
Possible Role of Mitochondrial Remodelling on Cellular Triacylglycerol Accumulation
Toshiyuki Kita et al.
JOURNAL OF BIOCHEMISTRY (2009)
Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion
Jarungjit Rujiviphat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Heterozygous Mutation of Opa1 in Drosophila Shortens Lifespan Mediated through Increased Reactive Oxygen Species Production
Sha Tang et al.
PLOS ONE (2009)
OPA1 Deficiency Associated with Increased Autophagy in Retinal Ganglion Cells in a Murine Model of Dominant Optic Atrophy
Kathryn E. White et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Hereditary optic neuropathies share a common mitochondrial coupling defect
Arnaud Chevrollier et al.
ANNALS OF NEUROLOGY (2008)
OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes
Patrizia Amati-Bonneau et al.
BRAIN (2008)
Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions:: a novel disorder of mtDNA maintenance
Gavin Hudson et al.
BRAIN (2008)
OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis
A. Olichon et al.
CELL DEATH AND DIFFERENTIATION (2007)
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
Christian Frezza et al.
CELL (2006)
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The essential amino acid lysine acts as precursor of glutamate in the mammalian central nervous system
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FEBS LETTERS (2001)
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
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NATURE GENETICS (2000)
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
C Alexander et al.
NATURE GENETICS (2000)