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Eamonn M. M. Quigley
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Supplemented Use of Pre-, Pro-, and Synbiotics in Severe Acute Pancreatitis: An Updated Systematic Review and Meta-Analysis of 13 Randomized Controlled Trials
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GENOMICS PROTEOMICS & BIOINFORMATICS (2018)
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NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
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Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic
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FRONTIERS IN MICROBIOLOGY (2017)
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Probiotics, Prebiotics, and Synbiotics for the Treatment and Prevention of Adult Dermatological Diseases
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AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2017)
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BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2016)
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Journal of Cystic Fibrosis (2016)
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Mariana de Araujo Etchepare et al.
LWT-FOOD SCIENCE AND TECHNOLOGY (2016)
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Optimization of electrospraying conditions for the microencapsulation of probiotics and evaluation of their resistance during storage and in-vitro digestion
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LWT-FOOD SCIENCE AND TECHNOLOGY (2016)
Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals
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TRENDS IN NEUROSCIENCES (2016)
Comparison of probiotic lactobacilli and bifidobacteria effects, immune responses and rotavirus vaccines and infection in different host species
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ACTA CHIMICA SLOVACA (2016)
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CARBOHYDRATE POLYMERS (2015)
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CURRENT OPINION IN BIOTECHNOLOGY (2015)
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Robert A. Rastall et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Characterization of freezing effect upon stability of, probiotic loaded, calcium-alginate microparticles
Sergio Sousa et al.
FOOD AND BIOPRODUCTS PROCESSING (2015)
Effect of salt on cell viability and membrane integrity of Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium longum as observed by flow cytometry
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FOOD MICROBIOLOGY (2015)
Effects of a novel encapsulating technique on the temperature tolerance and anti-colitis activity of the probiotic bacterium Lactobacillus kefiranofaciens M1
Sheng-Yao Wang et al.
FOOD MICROBIOLOGY (2015)
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FOOD MICROBIOLOGY (2015)
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A. R. Bhat et al.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2015)
Improved viability of Lactobacillus acidophilus NRRL-B 4495 during freeze-drying in whey protein-pullulan microcapsules
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JOURNAL OF MICROENCAPSULATION (2015)
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Annachiara De Prisco et al.
LWT-FOOD SCIENCE AND TECHNOLOGY (2015)
Microencapsulation of Lactobacillus plantarum (MTCC 5422) with fructooligosaccharide as wall material by spray drying
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LWT-FOOD SCIENCE AND TECHNOLOGY (2015)
Microencapsulation of Lactobacillus acidophilus LA-5, Bifidobacterium animalis subsp lactis BB-12 and Propionibacterium jensenii 702 by spray drying in goat's milk
C. Senaka Ranadheera et al.
SMALL RUMINANT RESEARCH (2015)
Preparation of Eleutherine americana-Alginate Complex Microcapsules and Application in Bifidobacterium longum
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BIOMED RESEARCH INTERNATIONAL (2015)
Developing a potential prebiotic of yogurt: growth of Bifidobacterium and yogurt cultures with addition of glycomacropeptide hydrolysate
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2015)
Effects of genetic, processing, or product formulation changes on efficacy and safety of probiotics
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ANNALS REPORTS (2014)
Activity of Encapsulated Lactobacillus bulgaricus in Alginate-whey Protein Microspheres
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BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY (2014)
Growth Characteristics Modeling of Lactobacillus acidophilus using RSM and ANN
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BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY (2014)
Protection of L. rhamnosus by spray-drying using two prebiotics colloids to enhance the viability
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CARBOHYDRATE POLYMERS (2014)
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CARBOHYDRATE POLYMERS (2014)
FROM OPTIMIZATION OF SYNBIOTIC MICROPARTICLES PREPARED BY SPRAY-DRYING TO DEVELOPMENT OF NEW FUNCTIONAL CARROT JUICE
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CHEMICAL INDUSTRY & CHEMICAL ENGINEERING QUARTERLY (2014)
Complex Coacervation as a Novel Microencapsulation Technique to Improve Viability of Probiotics Under Different Stresses
Loulouda A. Bosnea et al.
FOOD AND BIOPROCESS TECHNOLOGY (2014)
Survival of microencapsulated Bifidobacterium longum in Cheddar cheese during production and storage
Khalie Mahamad Amine et al.
FOOD CONTROL (2014)
Lactobacillus plantarum protection by entrapment in whey protein isolate: κ-carrageenan complex coacervates
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FOOD HYDROCOLLOIDS (2014)
Probiotic edible films as a new strategy for developing functional bakery products: The case of pan bread
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FOOD HYDROCOLLOIDS (2014)
Fluidized bed microencapsulation of Lactobacillus reuteri with sweet whey and shellac for improved acid resistance and in-vitro gastro-intestinal survival
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FOOD RESEARCH INTERNATIONAL (2014)
Entrapment, survival and release of Bifidobacterium adolescentis within chickpea protein-based microcapsules
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FOOD RESEARCH INTERNATIONAL (2014)
Effect of microencapsulation of Lactobacillus acidophilus LA-5 on physicochemical, sensory and microbiological characteristics of stirred probiotic yoghurt
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FOOD RESEARCH INTERNATIONAL (2014)
Effects of encapsulation on the viability of potential probiotic Lactobacillus plantarum exposed to high acidity condition and presence of bile salts
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FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL (2014)
Functional Pecorino cheese production by using innovative lamb rennet paste
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INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2014)
Effects of Lactobacillus plantarum immobilization in alginate coated with chitosan and gelatin on antibacterial activity
Imen Trabelsi et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)
Preparation and optimization of soy protein isolate-high methoxy pectin microcapsules loaded with Lactobacillus delbrueckii
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2014)
Evaluation of physiochemical, textural, microbiological and sensory characteristics in set yogurt reinforced by microencapsulated Bifidobacterium bifidum F-35
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2014)
Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gels
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INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Microencapsulation of Lactobacillus acidophilus La-5 by spray-drying using sweet whey and skim milk as encapsulating materials
G. M. Maciel et al.
JOURNAL OF DAIRY SCIENCE (2014)
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JOURNAL OF FOOD ENGINEERING (2014)
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Abbas Ahmadi et al.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2014)
Microencapsulation of Lactobacillus casei by spray drying
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JOURNAL OF MICROENCAPSULATION (2014)
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KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES (2014)
Co-encapsulation of probiotics with prebiotics on alginate matrix and its effect on viability in simulated gastric environment
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LWT-FOOD SCIENCE AND TECHNOLOGY (2014)
Viability of Lactobacillus plantarum entrapped in double emulsion during Oaxaca cheese manufacture, melting and simulated intestinal conditions
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LWT-FOOD SCIENCE AND TECHNOLOGY (2014)
Supercritical CO2 interpolymer complex encapsulation improves heat stability of probiotic bifidobacteria
M. S. Thantsha et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2014)
Microencapsulation of Lactobacillus acidophilus in zein-alginate core-shell microcapsules via electrospraying
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JOURNAL OF FUNCTIONAL FOODS (2014)
Probiotic functional foods: Survival of probiotics during processing and storage
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JOURNAL OF FUNCTIONAL FOODS (2014)
In vitro studies of modulation of pathogenic and probiotic bacterial proliferation and adhesion to intestinal cells by blackcurrant juices
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JOURNAL OF FUNCTIONAL FOODS (2014)
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CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2013)
Influence of Osmotic Stress and Encapsulating Materials on the Stability of Autochthonous Lactobacillus plantarum after Spray Drying
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DRYING TECHNOLOGY (2013)
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DRYING TECHNOLOGY (2013)
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FOLIA MICROBIOLOGICA (2013)
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FOOD CHEMISTRY (2013)
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FOOD RESEARCH INTERNATIONAL (2013)
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FOOD RESEARCH INTERNATIONAL (2013)
Co- encapsulation of Lactobacillus acidophilus with inulin or polydextrose in solid lipid microparticles provides protection and improves stability
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FOOD RESEARCH INTERNATIONAL (2013)
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FOOD RESEARCH INTERNATIONAL (2013)
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Microencapsulation of bifidobacteria by spray drying in the presence of prebiotics
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JOURNAL OF DAIRY SCIENCE (2012)
Encapsulation of probiotic bacteria in lamb rennet paste: Effects on the quality of Pecorino cheese
A. Santillo et al.
JOURNAL OF DAIRY SCIENCE (2012)
Bifidobacterium Bb-12 microencapsulated by spray drying with whey: Survival under simulated gastrointestinal conditions, tolerance to NaCl, and viability during storage
Fabiane Picinin De Castro-Cislaghi et al.
JOURNAL OF FOOD ENGINEERING (2012)
Application of whey protein micro-bead coatings for enhanced strength and probiotic protection during fruit juice storage and gastric incubation
S. B. Doherty et al.
JOURNAL OF MICROENCAPSULATION (2012)
Effect of microencapsulation of Lactobacillus salivarus 29 into alginate/chitosan/alginate microcapsules on viability and cytokine induction
Prati Bajracharya et al.
JOURNAL OF MICROENCAPSULATION (2012)
Structure, function and diversity of the healthy human microbiome
Curtis Huttenhower et al.
NATURE (2012)
Probiotic meat products and human nutrition
Danuta Kolozyn-Krajewska et al.
PROCESS BIOCHEMISTRY (2012)
Preparation and Characterization of Alginate and Psyllium Beads Containing Lactobacillus acidophilus
Farzaneh Lotfipour et al.
SCIENTIFIC WORLD JOURNAL (2012)
Single droplet drying for optimal spray drying of enzymes and probiotics
Maarten A. I. Schutyser et al.
TRENDS IN FOOD SCIENCE & TECHNOLOGY (2012)
Functional properties of free and encapsulated Lactobacillus reuteri DPC16 during and after passage through a simulated gastrointestinal tract
Qian Zhao et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2012)
Effect of whey protein-alginate wall systems on survival of microencapsulated Lactobacillus plantarum in simulated gastrointestinal conditions
R. Rajam et al.
JOURNAL OF FUNCTIONAL FOODS (2012)
Effect of cryopreservation and microencapsulation of lactic acid bacterium Enterococcus faecium MC13 for long-term storage
Paulraj Kanmani et al.
BIOCHEMICAL ENGINEERING JOURNAL (2011)
Viability of probiotic microorganisms in cheese during production and storage: a review
Reza Karimi et al.
DAIRY SCIENCE & TECHNOLOGY (2011)
Investigation of the factors influencing the survival of Bifidobacterium longum in model acidic solutions and fruit juices
Sawaminee Nualkaekul et al.
FOOD CHEMISTRY (2011)
Development and characterisation of whey protein micro-beads as potential matrices for probiotic protection
S. B. Doherty et al.
FOOD HYDROCOLLOIDS (2011)
Survival of probiotic lactobacilli in the upper gastrointestinal tract using an in vitro gastric model of digestion
Alberto Lo Curto et al.
FOOD MICROBIOLOGY (2011)
Review Article: Technological Aspects of Prebiotics in Probiotic Fermented Milks
R. Mohammadi et al.
FOOD REVIEWS INTERNATIONAL (2011)
How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences
Lorena Ruiz et al.
GENES AND NUTRITION (2011)
Microencapsulation of probiotic bacteria using pH-induced gelation of sodium caseinate and gellan gum
Arup Nag et al.
INTERNATIONAL DAIRY JOURNAL (2011)
Influence of L-cysteine, oxygen and relative humidity upon survival throughout storage of probiotic bacteria in whey protein-based microcapsules
D. Rodrigues et al.
INTERNATIONAL DAIRY JOURNAL (2011)
Encapsulation of probiotic Bifidobacterium longum BIOMA 5920 with alginate-human-like collagen and evaluation of survival in simulated gastrointestinal conditions
Ran Su et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2011)
Survivability of probiotics encapsulated in alginate gel microbeads using a novel impinging aerosols method
Asma Sohail et al.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2011)
Microencapsulation of Bifidobacterium bifidum F-35 in reinforced alginate microspheres prepared by emulsification/internal gelation
Qiang Zou et al.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2011)
Pea protein-based capsules for probiotic and prebiotic delivery
Karla J. Klemmer et al.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2011)
Enhanced Survival of Probiotic Lactobacillus acidophilus by Encapsulation with Nanostructured Polyelectrolyte Layers through Layer-by-Layer Approach
Angel J. Priya et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)
Effect of microencapsulation on survival of Lactobacillus plantarum in simulated gastrointestinal conditions, refrigeration, and yogurt
Graziela Brusch Brinques et al.
JOURNAL OF FOOD ENGINEERING (2011)
Comparison of different methods for release of Bifidobacterium longum Bb46 from the poly(vinylpyrrolidone)-poly(vinylacetate-co-crotonic acid) interpolymer complex matrix, and the effect of grinding on the microparticles
M. S. Thantsha et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2011)
Synbiotics in Health and Disease
Sofia Kolida et al.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 2 (2011)
Resistance of Microencapsulated Lactobacillus acidophilus LA1 to Processing Treatments and Simulated Gut Conditions
Latha Sabikhi et al.
FOOD AND BIOPROCESS TECHNOLOGY (2010)
Non-dairy probiotic products
Yadira Rivera-Espinoza et al.
FOOD MICROBIOLOGY (2010)
Textural properties of alginate-pectin beads and survivability of entrapped Lb. casei in simulated gastrointestinal conditions and in yoghurt
O. Sandoval-Castilla et al.
FOOD RESEARCH INTERNATIONAL (2010)
Viability of microencapsulated Bifidobacterium animalis ssp lactis BB12 in kefir during refrigerated storage
Fernando Gonzalez-Sanchez et al.
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2010)
Production of functional probiotic, prebiotic, and synbiotic ice creams
T. Di Criscio et al.
JOURNAL OF DAIRY SCIENCE (2010)
Influence of casein-based microencapsulation on freeze-drying and storage of probiotic cells
Thomas Heidebach et al.
JOURNAL OF FOOD ENGINEERING (2010)
Improving the Stability of Probiotic Bacteria in Model Fruit Juices Using Vitamins and Antioxidants
N. P. Shah et al.
JOURNAL OF FOOD SCIENCE (2010)
The probiotic paradox: live and dead cells are biological response modifiers
Clifford A. Adams
NUTRITION RESEARCH REVIEWS (2010)
Metabolic impact and potential exploitation of the stress reactions in lactobacilli
Diana I. Serrazanetti et al.
FOOD MICROBIOLOGY (2009)
Meta-Analysis: Lactobacillus Containing Quadruple Therapy Versus Standard Triple First-Line Therapy for Helicobacter pylori Eradication
Jian Zou et al.
HELICOBACTER (2009)
Improving the viability of Bifidobacterium bifidum BB-12 and Lactobacillus acidophilus LA-5 in white-brined cheese by microencapsulation
Barbaros Ozer et al.
INTERNATIONAL DAIRY JOURNAL (2009)
Functionality of freeze-dried L. casei cells immobilized on wheat grains
Loulouda A. Bosnea et al.
LWT-FOOD SCIENCE AND TECHNOLOGY (2009)
Fermentative ability of alginate-prebiotic encapsulated Lactobacillus acidophilus and survival under simulated gastrointestinal conditions
Filomena Nazzaro et al.
JOURNAL OF FUNCTIONAL FOODS (2009)
Effect of microencapsulation and resistant starch on the probiotic survival and sensory properties of synbiotic ice cream
A. Homayouni et al.
FOOD CHEMISTRY (2008)
Effect of Microencapsulation on Viability ofLactobacillus acidophilusLA-5 andBifidobacterium bifidumBB-12 During Kasar Cheese Ripening
BARBAROS ZER et al.
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2008)
Inactivation mechanisms of lactic acid starter cultures preserved by drying processes
C. Santivarangkna et al.
JOURNAL OF APPLIED MICROBIOLOGY (2008)
Viability of Lactobacillus rhamnosus R0011 in an apple-based fruit juice under simulated storage conditions at the consumer level
C. P. Champagne et al.
JOURNAL OF FOOD SCIENCE (2008)
Probiotics in fermented sausages
Luc De Vuyst et al.
MEAT SCIENCE (2008)
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
Harry Sokol et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Live encapsulated Lactobacillus acidophilus cells in yogurt for therapeutic oral delivery:: preparation and in vitro analysis of alginate-chitosan microcapsules
Aleksandra Malgorzata Urbanska et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2007)
Assessing the acid tolerance and the technological robustness of probiotic cultures for fortification in fruit juices
Vivien M. Sheehan et al.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2007)
Microencapsulation for the improved delivery of bioactive compounds into foods
Claude P. Champagne et al.
CURRENT OPINION IN BIOTECHNOLOGY (2007)
Packaging system and probiotic dairy foods
Adriano G. da Cruz et al.
FOOD RESEARCH INTERNATIONAL (2007)
Flow cytometry assessment of Lactobacillus rhamnosus GG (ATCC 53103) response to non-electrolytes stress
E. O. Sunny-Roberts et al.
NUTRITION & FOOD SCIENCE (2007)
Microbiological and sensory quality of dry fermented sausages containing alginate-microencapsulated Lactobacillus reuteri
Parthiban Mutbukumarasamy et al.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2006)
Effect of carbohydrates on the survival of Lactobacillus helveticus during vacuum drying
C Santivarangkna et al.
LETTERS IN APPLIED MICROBIOLOGY (2006)
Determination of survival, identity and stress resistance of probiotic bifidobacteria in bio-yoghurts
VS Jayamanne et al.
LETTERS IN APPLIED MICROBIOLOGY (2006)
Effect of cryoprotectants, prebiotics and microencapsulation on survival of probiotic organisms in yoghurt and freeze-dried yoghurt
P Capela et al.
FOOD RESEARCH INTERNATIONAL (2006)
Stability of Lactobacillus reuteri in different types of microcapsules
P Muthukumarasamy et al.
JOURNAL OF FOOD SCIENCE (2006)
Cellular injuries and storage stability of spray-dried Lactobacillus rhamnosus GG
E Ananta et al.
INTERNATIONAL DAIRY JOURNAL (2005)
Probiotic bacteria may become dormant during storage
SJ Lahtinen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
Acid and bile tolerance and cholesterol removal ability of lactobacilli strains
MT Liong et al.
JOURNAL OF DAIRY SCIENCE (2005)
Effects of various sugars added to growth and drying media upon thermotolerance and survival throughout storage of freeze-dried lactobacillus delbrueckii ssp bulgaricus
AS Carvalho et al.
BIOTECHNOLOGY PROGRESS (2004)
Stationary-phase acid and heat treatments for improvement of the viability of probiotic lactobacilli and bifidobacteria
M Saarela et al.
JOURNAL OF APPLIED MICROBIOLOGY (2004)
Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation
CM Galdeano et al.
JOURNAL OF APPLIED MICROBIOLOGY (2004)
Environmental stress responses in Lactobacillus: A review
M De Angelis et al.
PROTEOMICS (2004)
Evidence on the role of protein biosynthesis in the induction of heat tolerance of Lactobacillus rhamnosus GG by pressure pre-treatment
E Ananta et al.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2004)
Viability and activity of bifidobacteria in yoghurt containing fructooligosaccharide during refrigerated storage
AS Akalin et al.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2004)
Growth of probiotic and traditional yogurt cultures in milk supplemented with whey protein hydrolysate
KA McComas et al.
JOURNAL OF FOOD SCIENCE (2003)
The control of dissolved oxygen content in probiotic yoghurts by alternative packaging materials
CW Miller et al.
PACKAGING TECHNOLOGY AND SCIENCE (2003)
Stress responses in lactic acid bacteria
M van de Guchte et al.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY (2002)
The influence of packaging materials on the dissolved oxygen content of probiotic yoghurt
CW Miller et al.
PACKAGING TECHNOLOGY AND SCIENCE (2002)
Survival of Ca-alginate microencapsulated Bifidobacterium spp. in milk and simulated gastrointestinal conditions
LT Hansen et al.
FOOD MICROBIOLOGY (2002)
Improved survival of Lactobacillus paracasei NFBC 338 in spray-dried powders containing gum acacia
C Desmond et al.
JOURNAL OF APPLIED MICROBIOLOGY (2002)
Hydrogen excretion upon ingestion of dairy products in lactose-intolerant male subjects: importance of the live flora
X Pelletier et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2001)
Taxonomy and important features of probiotic microorganisms in food and nutrition
WH Holzapfel et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2001)
Environmental adaptation of probiotic lactobacilli towards improvement of performance during spray drying
C Desmond et al.
INTERNATIONAL DAIRY JOURNAL (2001)
Stabilization and preservation of Lactobacillus acidophilus in saccharide matrices
PB Conrad et al.
CRYOBIOLOGY (2000)
Growth and viability of commercial Bifidobacterium spp in skim milk containing oligosaccharides and inulin
HS Shin et al.
JOURNAL OF FOOD SCIENCE (2000)
Probiotic bacteria: Selective enumeration and survival in dairy foods
NP Shah
JOURNAL OF DAIRY SCIENCE (2000)
Cryoprotectants lead to phenotypic adaptation to freeze-thaw stress in Lactobacillus delbrueckii ssp bulgaricus CIP 101027T
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CRYOBIOLOGY (2000)
Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution
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