4.8 Article

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Toward Minimal Residual Disease-Directed Therapy in Melanoma

Florian Rambow et al.

Article Genetics & Heredity

Genetic determinants and epigenetic effects of pioneer-factor occupancy

Julie Donaghey et al.

NATURE GENETICS (2018)

Article Multidisciplinary Sciences

SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling

Thomas Strub et al.

NATURE COMMUNICATIONS (2018)

Article Biochemical Research Methods

scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data

Luyi Tian et al.

PLOS COMPUTATIONAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

Xiangjun Kong et al.

NATURE (2017)

Article Multidisciplinary Sciences

Rare cell variability and drug- induced reprogramming as a mode of cancer drug resistance

Sydney M. Shaffer et al.

NATURE (2017)

Article Multidisciplinary Sciences

Tracing the origins of relapse in acute myeloid leukaemia to stem cells

Liran I. Shlush et al.

NATURE (2017)

Article Multidisciplinary Sciences

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer et al.

NATURE (2017)

Review Multidisciplinary Sciences

The cancer epigenome: Concepts, challenges, and therapeutic opportunities

Mark A. Dawson

SCIENCE (2017)

Article Multidisciplinary Sciences

Click chemistry enables preclinical evaluation of targeted epigenetic therapies

Dean S. Tyler et al.

SCIENCE (2017)

Article Cell & Tissue Engineering

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance

Brian B. Liau et al.

CELL STEM CELL (2017)

Article Biochemical Research Methods

A rapid method to verify single-cell deposition setup for cell sorters

Olivia Roos Rodrigues et al.

CYTOMETRY PART A (2016)

Article Biochemistry & Molecular Biology

Chromatin Scanning by Dynamic Binding of Pioneer Factors

Kenneth S. Zaret et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

A 17-gene stemness score for rapid determination of risk in acute leukaemia

Stanley W. K. Ng et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

Sheng Li et al.

NATURE MEDICINE (2016)

Article Biochemistry & Molecular Biology

Functional interdependence of BRD4 and DOT1L in MLL leukemia

Omer Gilan et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Functional interdependence of BRD4 and DOT1L in MLL leukemia

Omer Gilan et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Cell & Tissue Engineering

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells

Carolyn A. De Graaf et al.

STEM CELL REPORTS (2016)

Article Biotechnology & Applied Microbiology

CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq

Tamar Hashimshony et al.

GENOME BIOLOGY (2016)

Article Biotechnology & Applied Microbiology

Pooling across cells to normalize single-cell RNA sequencing data with many zero counts

Aaron T. L. Lun et al.

GENOME BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance

Willy Hugo et al.

Article Multidisciplinary Sciences

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Philipp Rathert et al.

NATURE (2015)

Article Multidisciplinary Sciences

BET inhibitor resistance emerges from leukaemia stem cells

Chun Yew Fong et al.

NATURE (2015)

Article Biotechnology & Applied Microbiology

Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

Junwei Shi et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia

Britta Will et al.

NATURE MEDICINE (2015)

Article Biochemical Research Methods

HISAT: a fast spliced aligner with low memory requirements

Daehwan Kim et al.

NATURE METHODS (2015)

Article Biochemical Research Methods

HTSeq-a Python framework to work with high-throughput sequencing data

Simon Anders et al.

BIOINFORMATICS (2015)

Article Biotechnology & Applied Microbiology

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell et al.

NATURE BIOTECHNOLOGY (2014)

Article Biochemistry & Molecular Biology

Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation

Kyong-Rim Kieffer-Kwon et al.

Review Biochemistry & Molecular Biology

Modification of Enhancer Chromatin: What, How, and Why?

Eliezer Calo et al.

MOLECULAR CELL (2013)

Review Oncology

Cancer drug resistance: an evolving paradigm

Caitriona Holohan et al.

NATURE REVIEWS CANCER (2013)

Review Genetics & Heredity

Transcription factors: from enhancer binding to developmental control

Francois Spitz et al.

NATURE REVIEWS GENETICS (2012)

Article Biochemical Research Methods

MEME-ChIP: motif analysis of large DNA datasets

Philip Machanick et al.

BIOINFORMATICS (2011)

Article Multidisciplinary Sciences

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber et al.

NATURE (2011)

Letter Biotechnology & Applied Microbiology

Integrative genomics viewer

James T. Robinson et al.

NATURE BIOTECHNOLOGY (2011)

Article Multidisciplinary Sciences

Targeting MYC dependence in cancer by inhibiting BET bromodomains

Jennifer A. Mertz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

Article Biochemical Research Methods

Fast and accurate long-read alignment with Burrows-Wheeler transform

Heng Li et al.

BIOINFORMATICS (2010)

Article Biochemical Research Methods

BEDTools: a flexible suite of utilities for comparing genomic features

Aaron R. Quinlan et al.

BIOINFORMATICS (2010)

Article Biochemistry & Molecular Biology

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Sreenath V. Sharma et al.

Review Genetics & Heredity

Chromatin structure and the inheritance of epigenetic information

Raphael Margueron et al.

NATURE REVIEWS GENETICS (2010)

Article Biotechnology & Applied Microbiology

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead et al.

GENOME BIOLOGY (2009)

Article Biotechnology & Applied Microbiology

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang et al.

GENOME BIOLOGY (2008)

Article Biochemical Research Methods

A probability-based approach for the analysis of large-scale RNAi screens

Renate Koenig et al.

NATURE METHODS (2007)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)