相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Extended Zinc AMBER Force Field (EZAFF)
Zhuoqin Yu et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2018)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers
H. Courtney Hodges et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers
H. Courtney Hodges et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
Rhamy Zeid et al.
NATURE GENETICS (2018)
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
Marielle E. Yohe et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma
Narendra Bharathy et al.
SCIENCE SIGNALING (2018)
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation
Kyong-Rim Kieffer-Kwon et al.
MOLECULAR CELL (2017)
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
Robin M. Meyers et al.
NATURE GENETICS (2017)
ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells
Horng D. Ou et al.
SCIENCE (2017)
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability
Berkley E. Gryder et al.
CANCER DISCOVERY (2017)
A Druggable TCF4-and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm
Michele Ceribelli et al.
CANCER CELL (2016)
MCPB.py: A Python Based Metal Center Parameter Builder
Pengfei Li et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2016)
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Charles Y. Lin et al.
NATURE (2016)
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin
Ballachanda N. Devaiah et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
CRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma
Michael P. Phelps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
Teru Hideshima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Development of a Potent and Selective HDAC8 Inhibitor
Oscar J. Ingham et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin
Ballachanda N. Devaiah et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL
Matthew C. Stubbs et al.
CLINICAL CANCER RESEARCH (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer
Edmond Chipumuro et al.
CELL (2014)
Lineage of origin in rhabdomyosarcoma informs pharmacological response
Jinu Abraham et al.
GENES & DEVELOPMENT (2014)
Genome-wide localization of small molecules
Lars Anders et al.
NATURE BIOTECHNOLOGY (2014)
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Katrina J. Falkenberg et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
David A. Orlando et al.
CELL REPORTS (2014)
Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
Bjoern Chapuy et al.
CANCER CELL (2013)
Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma
Xiang Chen et al.
CANCER CELL (2013)
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability
Benjamin E. L. Lauffer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
Jason D. Buenrostro et al.
NATURE METHODS (2013)
Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Alexandre Puissant et al.
CANCER DISCOVERY (2013)
Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed
Berkley E. Gryder et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
Peter J. Watson et al.
NATURE (2012)
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
Warren A. Whyte et al.
NATURE (2012)
Epigenetic protein families: a new frontier for drug discovery
Cheryl H. Arrowsmith et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening
Patrick J. Grohar et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Chemical phylogenetics of histone deacetylases
James E. Bradner et al.
NATURE CHEMICAL BIOLOGY (2010)
The art of the chemical probe
Stephen V. Frye
NATURE CHEMICAL BIOLOGY (2010)
Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
Zhibin Wang et al.
CELL (2009)
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
Joey L. Methot et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
Histone acetylation increases chromatin accessibility
SM Görisch et al.
JOURNAL OF CELL SCIENCE (2005)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
On the function of the 14 Å long internal cavity of histone deacetylase-like protein:: Implications for the design of histone deacetylase inhibitors
DF Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
MG Guenther et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)