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Scott J. Rodig et al.
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Whijae Roh et al.
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Rajasekharan Somasundaram et al.
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Antje Sucker et al.
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Tahira Devji et al.
JAMA ONCOLOGY (2017)
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Antoni Ribas et al.
CELL (2017)
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening
E. Robert McDonald et al.
CELL (2017)
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
Padmanee Sharma et al.
CELL (2017)
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
Jianjun Gao et al.
CELL (2016)
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Joseph L. Benci et al.
CELL (2016)
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Willy Hugo et al.
CELL (2016)
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Jonathan M. Pitt et al.
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LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors
Ying Cheng et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Landscape of tumor-infiltrating T cell repertoire of human cancers
Bo Li et al.
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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
Jesse M. Zaretsky et al.
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Megan Lyle et al.
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Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells
Shu Wang et al.
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Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
Nicholas McGranahan et al.
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Targeted Therapy and Checkpoint Immunotherapy Combinations for the Treatment of Cancer
Paul E. Hughes et al.
TRENDS IN IMMUNOLOGY (2016)
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Vinit Kumar et al.
TRENDS IN IMMUNOLOGY (2016)
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
Shohei Koyama et al.
NATURE COMMUNICATIONS (2016)
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy
Douglas B. Johnson et al.
NATURE COMMUNICATIONS (2016)
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
Suzanne L. Topalian et al.
NATURE REVIEWS CANCER (2016)
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Sebastian Kreiter et al.
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Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
Eliezer M. Van Allen et al.
SCIENCE (2015)
SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway
Qiao-Yang Sun et al.
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LNK (SH2B3): paradoxical effects in ovarian cancer
L-W Ding et al.
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Ynto S. de Boer et al.
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Genetic loss of SH2B3 in acute lymphoblastic leukemia
Arianne Perez-Garcia et al.
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Alan C. Geller et al.
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Mutational heterogeneity in cancer and the search for new cancer-associated genes
Michael S. Lawrence et al.
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Safety and Tumor Responses with Lambrolizumab (Anti-PD-1) in Melanoma
Omid Hamid et al.
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Role of the adaptor protein LNK in normal and malignant hematopoiesis
S. Gery et al.
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DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications
Hsin-An Hou et al.
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14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells
Jing Jiang et al.
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IFN-α in the Treatment of Melanoma
Ahmad A. Tarhini et al.
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Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
Keith T. Flaherty et al.
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The adaptor Lnk (SH2B3): An emerging regulator in vascular cells and a link between immune and inflammatory signaling
Julie Devalliere et al.
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Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
Paul B. Chapman et al.
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Lnk constrains myeloproliferative diseases in mice
Alexey Bersenev et al.
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LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
A. Pardanani et al.
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LNK Mutations in JAK2 Mutation-Negative Erythrocytosis.
Terra L. Lasho et al.
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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
Keith T. Flaherty et al.
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Sigal Gery et al.
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Newly identified genetic risk variants for celiac disease related to the immune response
Karen A. Hunt et al.
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Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
AV Jones et al.
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Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
W Tong et al.
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Mechanisms of Interferon-alpha induced apoptosis in malignant cells
L Thyrell et al.
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