相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Zita Hubler et al.
NATURE (2018)
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states
Ioannis Manolaridis et al.
NATURE (2018)
Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease
Bitna Yi et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Dendrogenin A drives LXR to trigger lethal autophagy in cancers
Gregory Segala et al.
NATURE COMMUNICATIONS (2017)
Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death
Julie Leignadier et al.
BIOCHEMICAL PHARMACOLOGY (2017)
Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1
Zachary Lee Johnson et al.
CELL (2017)
Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design
Tatiana Y. Hargrove et al.
JOURNAL OF LIPID RESEARCH (2016)
Crystal structure of the human σ1 receptor
Hayden R. Schmidt et al.
NATURE (2016)
Crystal structure of the epithelial calcium channel TRPV6
Kei Saotome et al.
NATURE (2016)
Structure of human Niemann-Pick C1 protein
Xiaochun Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
DHCR7: A vital enzyme switch between cholesterol and vitamin D production
Anika V. Prabhu et al.
PROGRESS IN LIPID RESEARCH (2016)
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer
Lu Zhang et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection
Feiran Lu et al.
ELIFE (2015)
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways
Matthew A. Mitsche et al.
ELIFE (2015)
Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum
Xiaochun Li et al.
NATURE (2015)
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Julia Kozlitina et al.
NATURE GENETICS (2014)
TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease
Luis Sanchez-Pulido et al.
FRONTIERS IN GENETICS (2014)
Clinical, molecular and biochemical characterization of nine Spanish families with Conradi-Hunermann-Happle syndrome: new insights into X-linked dominant chondrodysplasia punctata with a comprehensive review of the literature
J. Canueto et al.
BRITISH JOURNAL OF DERMATOLOGY (2012)
A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma
Jeffrey G. McDonald et al.
JOURNAL OF LIPID RESEARCH (2012)
Biosynthesis of Cholesterol and Other Sterols
W. David Nes
CHEMICAL REVIEWS (2011)
Malformation syndromes caused by disorders of cholesterol synthesis
Forbes D. Porter et al.
JOURNAL OF LIPID RESEARCH (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation
Philippe de Medina et al.
AUTOPHAGY (2009)
Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism
P. de Medina et al.
CELL DEATH AND DIFFERENTIATION (2009)
The pharmacology of sigma-1 receptors
Tangui Maurice et al.
PHARMACOLOGY & THERAPEUTICS (2009)
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Stephen G. Aller et al.
SCIENCE (2009)
Identification of essential amino acid residues in a sterol 8,7-isomerase from Zea mays reveals functional homology and diversity with the isomerases of animal and fungal origin
Alain Rahier et al.
BIOCHEMICAL JOURNAL (2008)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells
William A. Barton et al.
PROTEIN SCIENCE (2006)
Discovery of high-affinity ligands of σ1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening
C Laggner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Enzymatic mechanisms for catalysis of enolization: ketosteroid isomerase
RM Pollack
BIOORGANIC CHEMISTRY (2004)
Purification, characterization and catalytic properties of human sterol 8-isomerase
WD Nes et al.
BIOCHEMICAL JOURNAL (2002)
Substructure solution with SHELXD
TR Schneider et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2002)
分享论文
