期刊
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
卷 49, 期 4, 页码 671-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cvsm.2019.02.007
关键词
Lyme disease; Canines; OspC; Ixodes ticks; Lyme vaccines; Borrelia; Lyme diagnostics; OspA
资金
- NIAID NIH HHS [R01 AI141801, R56 AI127801, R01 AI067746] Funding Source: Medline
The Lyme disease spirochetes are a highly diverse group of bacteria with unique biological properties. Their ability to cycle between ticks and mammals requires that they adapt to variable and constantly changing environmental conditions. Outer surface protein C is an essential virulence determinant that has received considerable attention in vaccine and diagnostic assay development. Knowledge of OspC diversity, its antigenic determinants, and its production patterns throughout the enzootic cycle, as well as in the laboratory setting, is essential for understanding immune responses induced by infection or vaccination.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据