期刊
TRENDS IN BIOTECHNOLOGY
卷 38, 期 1, 页码 83-98出版社
CELL PRESS
DOI: 10.1016/j.tibtech.2019.06.003
关键词
-
资金
- European Union [739572]
- ERC Grant CoG MagTendon [772817]
- Fundacao para a Ciencia e a Tecnologia (FCT) [PD/BD/128088/2016]
- European Regional Development Fund (ERDF) [NORTE-01-0145-FEDER-000021]
- European Research Council (ERC) [772817] Funding Source: European Research Council (ERC)
- Fundação para a Ciência e a Tecnologia [PD/BD/128088/2016] Funding Source: FCT
Musculoskeletal diseases are increasing the prevalence of physical disability worldwide. Within the body, musculoskeletal soft and hard tissues integrate through specific multitissue transitions, allowing for body movements. Owing to their unique compositional and structural gradients, injuries challenge the native interfaces and tissue regeneration is unlikely to occur. TISSUE engineering strategies are emerging to emulate the physiological environment of soft-to-hart tissue interfaces. Advances in biomaterial design enable control over biophysical parameters , but biomaterials alone are not sufficient to provide adequate support and guide transplanted cells. Therefore, biological, biophysical, and biochemical tools can be integrated into a multifactorial toolbox, steering prospective advances toward engineering clinically relevant soft-to-hart tissue interfaces.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据