期刊
TETRAHEDRON LETTERS
卷 60, 期 24, 页码 1604-1606出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2019.05.026
关键词
Paralemnolin C; Asymmetric total synthesis; Absolute configuration; Biological study
资金
- Platform for Drug Discovery, Informatics, and Structural Life Science from the Ministry of Education, Culture, Sports, Science and Technology, Japan
The first asymmetric total synthesis of paralemnolin C was achieved. The absolute configuration at C11 of this natural product was determined from the X-ray crystallographic analysis of the epoxide derivative. In addition, biological studies of eremophilane derivatives including paralemnolin C and sagittacin E were carried out. (C) 2019 Elsevier Ltd. All rights reserved.
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