期刊
SYNTHETIC COMMUNICATIONS
卷 49, 期 20, 页码 2642-2650出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2019.1637894
关键词
Alkylation; esterification; microwave; phosphonate; phosphonic acid; phosphonic monoester
资金
- National Research, Development and Innovation Office [K119202]
- Gedeon Richter's Talentum Foundation
- Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [BO/00130/19/7]
Possibilities for the mono- and diesterification of phenylphosphonic acid were evaluated considering the microwave(MW)-assisted direct esterification, and the alkylating esterification. It was found that regarding the monoesterification, the reaction with 15-fold alcohol excess in the presence of [bmim][BF4] additive utilizing MWs is superior than the approach by alkylation. At the same time, for the conversion of the monoester intermediate to the diester, the reaction with alkyl halides in the presence of triethylamine as the base, again under MW irradiation, was found to be the method of choice. Phosphonates with both identical and different alkoxy groups were made available. [GRAPHICS]
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据