期刊
SYNLETT
卷 30, 期 15, 页码 1738-1764出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1611875
关键词
carbonyl-ene reactions; biaryl ligands; bis(oxazoline) ligands; Schiff base ligands; salen ligands; N,N '-dioxide ligands
资金
- University of Kashan
The carbonyl-ene reaction is one of the most well-known reactions for C-C bond formation. Based on frontier molecular orbitals (FMO), carbonyl-ene reactions occur between the highest occupied molecular orbital (HOMO) of the ene compound bearing an active hydrogen atom at the allylic center and the lowest unoccupied molecular orbital (LUMO) of the electron-deficient enophile, which is a carbonyl compound. A high activation barrier enforces the concerted ene reaction rather than a Diels-Alder reaction at high temperature. Employing a catalytic system can eliminate defects in the ene reaction, and chiral catalysts promote the reaction under mild conditions to produce optically active compounds. In this account, we highlight investigations on the effects of various classes of chiral ligands on intermolecular and intramolecular carbonyl-ene reactions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据