期刊
SCIENCE
卷 365, 期 6451, 页码 393-396出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aax0379
关键词
-
资金
- Bio-oriented Technology Research Advancement Institution, NARO (Research Program on Development of Innovative Technology) [29009B]
- NARO (Precedence and Trial Research Project of NARO)
The genetic variation of rice cultivars provides a resource for further varietal improvement through breeding. Some rice varieties are sensitive to benzobicyclon (BBC), a beta-triketone herbicide that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD). Here we identify a rice gene, HIS1 (HPPD INHIBITOR SENSITIVE 1), that confers resistance to BBC and other beta-triketone herbicides. We show that HIS1 encodes an Fe(II)/2-oxoglutarate-dependent oxygenase that detoxifies beta-triketone herbicides by catalyzing their hydroxylation. Genealogy analysis revealed that BBC-sensitive rice variants inherited a dysfunctional his1 allele from an indica rice variety. Forced expression of HIS1 in Arabidopsis conferred resistance not only to BBC but also to four additional beta-triketone herbicides. HIS1 may prove useful for breeding herbicide-resistant crops.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据