期刊
RUSSIAN CHEMICAL BULLETIN
卷 68, 期 5, 页码 1031-1035出版社
SPRINGER
DOI: 10.1007/s11172-019-2515-2
关键词
organosulfur compounds; sulfi des; monoterpenoids; pinane derivatives; platelets; antiaggregation and anticoagulant activity
Pinane sulfi de obtained by the addition of methyl hydrosulfanylacetate at the double bond of -pinene inhibits platelet receptor activity. It inhibits completely platelet aggregation induced by adrenaline, ADP, collagen, arachidonic acid, and also reduces the eff ect of ristomycin. This compound inhibits both platelet and coagulation hemostasis, which allows one to use it for creation promising antiaggregation drugs and for stabilization blood products.
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