期刊
RESEARCH IN MICROBIOLOGY
卷 170, 期 8, 页码 407-416出版社
ELSEVIER
DOI: 10.1016/j.resmic.2019.06.003
关键词
CydDC; ABC transporter; Redox; Thiol; E. coli
类别
资金
- Biotechnology and Biological Sciences Research Council (BBSRC), UK [BB/M0225791/1, BB/H016805/1]
- Leverhulme Trust [RPG-20130041]
- BBSRC [BB/H016805/1] Funding Source: UKRI
The CydDC family of ABC transporters export the low molecular weight thiols glutathione and cysteine to the periplasm of a variety of bacterial species. The CydDC complex has previously been shown to be important for disulfide folding, motility, respiration, and tolerance to nitric oxide and antibiotics. In addition, CydDC is thus far unique amongst ABC transporters in that it binds a haem cofactor that appears to modulate ATPase activity. CydDC has a diverse impact upon bacterial metabolism, growth, and virulence, and is of interest to those working on membrane transport mechanisms, redox biology, aerobic respiration, and stress sensing/tolerance during infection. (C) 2019 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据