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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Qian Han et al.
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David R. Wise et al.
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Assay and purification of ω-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the α-keto acid analogues of glutamine and asparagine
Boris F. Krasnikov et al.
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pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I
Q Han et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)