期刊
PHYSIOLOGY
卷 34, 期 4, 页码 264-282出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00057.2018
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资金
- First Faculty of Medicine, the Medical University of Warsaw, Warsaw, Poland
- British Heart Foundation (BHF)
- BHF program [RG/12/6/29670]
The carotid body has emerged as a therapeutic target for cardio-respiratory-metabolic diseases. With the expansive functions of the chemoreflex, we sought mechanisms to explain differential control of individual responses. We purport a remarkable correlation between phenotype of a chemosensory unit (glomus cell-sensory afferent) with a distinct component of the reflex response. This logic could permit differential modulation of distinct chemoreflex responses, a strategy ideal for therapeutic exploitation.
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