期刊
PHYSICS OF LIFE REVIEWS
卷 30, 期 -, 页码 1-18出版社
ELSEVIER
DOI: 10.1016/j.plrev.2019.06.002
关键词
Functional segregation; Brain organization; Brain asymmetry; Atypical language lateralization; Functional lateralization; Language dominance
资金
- Fonds Wetenschappelijk Onderzoek Vlaanderen [G.0555.11, G.01114.16N]
Directional hemispheric dominance has been established for numerous cognitive functions in the human brain. Strong population biases with some functions favoring the left and others the right hemisphere generated the popular idea of an advantageous prototypical division of labor between both halves of the brain, molded by evolution and genetically blueprinted. As most empirical studies on functional lateralization focused on a single function at a time, little is known about the relation between different asymmetric functions and the consequences of atypical functional segregation in healthy individuals. Recent investigations suggest the existence of at least three different phenotypes in human functional segregation relevant for future neuroscientific and genetic research. Using atypical language dominance as a starting point, I summarize the existing literature about its behavioral and neural consequences and explore the evidence for intermediate phenotypes in brain functional segregation that could bridge behavioral and genetic data. (C) 2019 Elsevier B.V. All rights reserved.
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