期刊
PHYSICS IN MEDICINE AND BIOLOGY
卷 64, 期 15, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/1361-6560/ab2cb0
关键词
time of flight positron emission tomography; depth of interaction; time resolution; time resolution of 10 ps; high resolution PET system
资金
- CERN Knowledge Transfer Funds
- CERN Medical Applications Funds
- H2020 Ascimat Project
- FAST COST Action [TD1401]
- TICAL ERC [338953]
The performance of a light sharing and recirculation mechanism that allows the extraction of depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In parallel, a method to optimize the coincidence time resolution (CTR) of PET detectors by use of the DOI information is proposed and tested. For these purposes, a dedicated 64-channels readout setup has been developed with intrinsic timing resolution of 16 ps FWHM. Several PET modules have been produced, based on LYSO:Ce scintillators and commercial silicon photomultiplier (SiPM) arrays, with 3 x 3 mm(2) individual SiPM size. The results show the possibility to achieve a timing resolution of 157 ps FWHM, combined with the already demonstrated spatial resolution of 1.5 mm FWHM, DOI resolution of 3 mm FWHM, and energy resolution of 9% FWHM at 511 keV, with 15 mm long crystals of section 1.53 x 1.53 mm(2) and 3.1 x 3.1 mm(2). At the same time, the extraction of the DOI coordinate has been demonstrated not to deteriorate the timing performance of the PET module.
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