期刊
ORGANIC LETTERS
卷 21, 期 15, 页码 6155-6159出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02361
关键词
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资金
- Nanjing Tech University [39837137, 39837101, 3827401739]
- National Natural Science Foundation of China [21372210, 21672198, 21801129]
- State Key Program of National Natural Science Foundation of China [21432009]
- Natural Science Research Projects in Jiangsu higher education institutions [18KJB150018]
- Ministry of Education of Singapore [MOE2016-T1-002-043, RGI11/16]
A regioselective and stereoselective difluoromethylation of enamides with bench-stable and easily accessible difluoromethyltriphenylphosphonium bromide is described. A broad array of synthetically important and geometrically defined beta-difluoromethylated enamides bearing various functional groups are obtained with up to 91% yield.
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