期刊
ORGANIC LETTERS
卷 21, 期 12, 页码 4864-4867出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01751
关键词
-
资金
- Natural Science Foundation of Hainan Province [2019CXTD411]
- Natural Science Foundation of China [41606088, 31672070]
- China Agriculture Research System [CARS-21]
- Ministry of Agriculture and Rural Affairs, P.R. of China (NFZX2018)
- Central Public-interest Scientific Institution Basal Research Fund for Chinese Academy of Tropical Agricultural Sciences [17CXTD-15, 1630052016008]
Four unusual indole-terpenoids, penerpenes A-D (1-4), along with two known ones paxilline (5) and emindole SB (6), were isolated from the marine-derived fungus Penicillium sp. KFD28. The absolute structures of 1-4 were elucidated on the basis of spectroscopic data and ECD spectra analysis along with quantum ECD calculations. Compounds 1 and 2 showed potent inhibitory activity toward protein tyrosine phosphatases (PTP1B and TCPTP). Plausible biosynthetic pathways of compounds 1-4 are proposed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据