期刊
ORGANIC LETTERS
卷 21, 期 12, 页码 4698-4702出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01578
关键词
-
资金
- National Natural Science Foundation of China [21871071]
- Major Scientific and Technological Innovation Project of Zhejiang [2019C01081]
The first example of oxidative C-H fluoroalkoxylation of quinoxalinones with fluoroalkyl alcohols under transition-metal and solvent-free conditions is described. This approach provides the synthesis of fluoroalkoxylated quinoxaline derivatives with good to excellent yields under mild reactions conditions. This method can also be extended to the facile and efficient synthesis of histamine-4 receptor.
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