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Julie Soutourina
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The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression
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Architecture of the RNA polymerase II-Mediator core initiation complex
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Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo
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Molecular architecture of the yeast Mediator complex
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ELIFE (2015)
RNA polymerase II contributes to preventing transcription-mediated replication fork stalls
Irene Felipe-Abrio et al.
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Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries
Yuko Kikuchi et al.
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Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex
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TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape
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Kin28 regulates the transient association of Mediator with core promoters
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Mediator links transcription and DNA repair by facilitating Rad2/XPG recruitment
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Extensive transcriptional heterogeneity revealed by isoform profiling
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XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethylation for Accurate Expression of Activated Genes
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Structure of the Mediator head module
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Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II
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DNA damage response and transcription
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Diverse Roles of RNA Polymerase II-associated Factor 1 Complex in Different Subpathways of Nucleotide Excision Repair
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Architecture of the Mediator head module
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Direct Interaction of RNA Polymerase II and Mediator Required for Transcription in Vivo
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NER Factors Are Recruited to Active Promoters and Facilitate Chromatin Modification for Transcription in the Absence of Exogenous Genotoxic Attack
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MOLECULAR CELL (2010)
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
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Yeast Rpb9 plays an important role in ubiquitylation and degradation of Rpb1 in response to UV-induced DNA damage
Xuefeng Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator
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XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: Implications for Cockayne syndrome in XP-G/CS patients
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Jesper Q. Svejstrup
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Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: Insights for transcription-coupled repair and Cockayne syndrome
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MOLECULAR CELL (2005)
Mediator and the mechanism of transcriptional activation
RD Kornberg
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Yeast RNA polymerase II lacking the Rpb9 subunit is impaired for interaction with transcription factor IIF
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Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae
SS Li et al.
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