相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Peng Chen et al.
SCIENCE (2018)
Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study
Bjoern Hellenkamp et al.
NATURE METHODS (2018)
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Nick S. Laursen et al.
SCIENCE (2018)
A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1
Kwok-ho Lam et al.
NATURE COMMUNICATIONS (2018)
Cross-Linking Mass Spectrometry: An Emerging Technology for Interactomics and Structural Biology
Clinton Yu et al.
ANALYTICAL CHEMISTRY (2018)
Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants
Pulkit Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection
M. H. Wilcox et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Developing a Multiplexed Quantitative Cross-Linking Mass Spectrometry Platform for Comparative Structural Analysis of Protein Complexes
Clinton Yu et al.
ANALYTICAL CHEMISTRY (2016)
A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection
Diane J. Schmidt et al.
CLINICAL AND VACCINE IMMUNOLOGY (2016)
Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
Liang Tao et al.
NATURE (2016)
The Tip of the Four N-Terminal -Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation
Carolina Varela Chavez et al.
TOXINS (2016)
Crystal structure of Clostridium difficile toxin A
Nicole M. Chumbler et al.
NATURE MICROBIOLOGY (2016)
Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides
Yongrong Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Exposure of Neutralizing Epitopes in the Carboxyl-terminal Domain of TcdB Is Altered by a Proximal Hypervariable Region
Jason L. Larabee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Burden of Clostridium difficile Infection in the United States
Fernanda C. Lessa et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections
Glen P. Carter et al.
MBIO (2015)
Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B
Pengfei Yuan et al.
CELL RESEARCH (2015)
Critical Roles of Clostridium difficile Toxin B Enzymatic Activities in Pathogenesis
Shan Li et al.
INFECTION AND IMMUNITY (2015)
Developing New Isotope-Coded Mass Spectrometry-Cleavable Cross-Linkers for Elucidating Protein Structures
Clinton Yu et al.
ANALYTICAL CHEMISTRY (2014)
Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile
Tomohiko Murase et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Mechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography
Peter Orth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice
Zhiyong Yang et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline
Alexander Leitner et al.
NATURE PROTOCOLS (2014)
Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore
Zhifen Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins
Bjoern Schorch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Combined Repetitive Oligopeptides of Clostridium difficile Toxin A Counteract Premature Cleavage of the Glucosyl-Transferase Domain by Stabilizing Protein Conformation
Alexandra Olling et al.
TOXINS (2014)
Improved low-resolution crystallographic refinement with Phenix and Rosetta
Frank DiMaio et al.
NATURE METHODS (2013)
A Segment of 97 Amino Acids within the Translocation Domain of Clostridium difficile Toxin B Is Essential for Toxicity
Yongrong Zhang et al.
PLOS ONE (2013)
Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments
Marko Swoboda et al.
ACS NANO (2012)
TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing
Jordi M. Lanis et al.
MOLECULAR MICROBIOLOGY (2012)
Botulinum Neurotoxin Is Shielded by NTNHA in an Interlocked Complex
Shenyan Gu et al.
SCIENCE (2012)
The role of toxin A and toxin B in the virulence of Clostridium difficile
Glen P. Carter et al.
TRENDS IN MICROBIOLOGY (2012)
Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism
Nicole M. Chumbler et al.
PLOS PATHOGENS (2012)
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Inositol Hexakisphosphate-dependent Processing of Clostridium sordellii Lethal Toxin and Clostridium novyi α-Toxin
Gregor Guttenberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Development of a Novel Cross-linking Strategy for Fast and Accurate Identification of Cross-linked Peptides of Protein Complexes
Athit Kao et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B
Selda Genisyuerek et al.
MOLECULAR MICROBIOLOGY (2011)
Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins
Aimee Shen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A
Isa Kreimeyer et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Optimizing Methods to Recover Absolute FRET Efficiency from Immobilized Single Molecules
James J. McCann et al.
BIOPHYSICAL JOURNAL (2010)
Rational Design of Inhibitors and Activity-Based Probes Targeting Clostridium difficile Virulence Factor TcdB
Aaron W. Puri et al.
CHEMISTRY & BIOLOGY (2010)
FRET Efficiency Distributions of Multistate Single Molecules
Irina V. Gopich et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
The role of toxin A and toxin B in Clostridium difficile infection
Sarah A. Kuehne et al.
NATURE (2010)
Structural organization of the functional domains of Clostridium difficile toxins A and B
Rory N. Pruitt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Identification of a conserved membrane localization domain within numerous large bacterial protein toxins
Brett Geissler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile
Jordi M. Lanis et al.
PLOS PATHOGENS (2010)
Inositol Hexakisphosphate-Induced Autoprocessing of Large Bacterial Protein Toxins
Martina Egerer et al.
PLOS PATHOGENS (2010)
Toxin B is essential for virulence of Clostridium difficile
Dena Lyras et al.
NATURE (2009)
Clostridium difficile infection: new developments in epidemiology and pathogenesis
Maja Rupnik et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium
Guilin Yang et al.
BMC MICROBIOLOGY (2008)
Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain
Patrick J. Lupardus et al.
SCIENCE (2008)
Structure and mode of action of clostridial glucosylating toxins: the ABCD model
Thomas Jank et al.
TRENDS IN MICROBIOLOGY (2008)
Auto-catalytic cleavage of Clostridium difficile toxins a and B depends on cysteine protease activity
Martina Egerer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
Christopher D. Putnam et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2007)
ATSAS 2.1 -: towards automated and web-supported small-angle scattering data analysis
Maxim V. Petoukhov et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Autocatalytic cleavage of Clostridium difficile toxin
Jessica Reineke et al.
NATURE (2007)
Toward the structural genomics of complexes:: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis
Michael Strong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Carbohydrate recognition by Clostridium difficile toxin A
A Greco et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A
JGS Ho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Structural basis for the function of Clostridium difficile toxin B
DJ Reinert et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity
B Mesmin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A novel solenoid fold in the cell wall anchoring domain of the pneumococcal virulence factor LytA
C Fernández-Tornero et al.
NATURE STRUCTURAL BIOLOGY (2001)
When protein folding is simplified to protein coiling: the continuum of solenoid protein structures
B Kobe et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
pH-induced conformational changes in Clostridium difficile toxin B
M Qa'Dan et al.
INFECTION AND IMMUNITY (2000)