相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci
Karsten B. Sieber et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)
Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study
Asahi Hishida et al.
AMERICAN JOURNAL OF NEPHROLOGY (2018)
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
Eric R. Gamazon et al.
NATURE GENETICS (2018)
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases
Masahiro Kanai et al.
NATURE GENETICS (2018)
Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations
Jeonghwan Lee et al.
PLOS ONE (2018)
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome
Christopher E. Gillies et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
An atlas of genetic associations in UK Biobank
Oriol Canela-Xandri et al.
NATURE GENETICS (2018)
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function
Man Li et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Sequential recruitment of study participants may inflate genetic heritability estimates
Damia Noce et al.
HUMAN GENETICS (2017)
Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution
Reedik Magi et al.
HUMAN MOLECULAR GENETICS (2017)
Changes in ceramide metabolism are essential in Madin-Darby canine kidney cell differentiation
Lucila Gisele Pescio et al.
JOURNAL OF LIPID RESEARCH (2017)
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy
Adeera Levin et al.
LANCET (2017)
Genetic effects on gene expression across human tissues
Francois Aguet et al.
NATURE (2017)
Voltage-gated calcium channels: Novel targets for cancer therapy
Nam Nhut Phan et al.
ONCOLOGY LETTERS (2017)
Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies
Christian Benner et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies
Roby Joehanes et al.
GENOME BIOLOGY (2017)
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity
Anubha Mahajan et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Novel regulations of MEF2-A, MEF2-D, and CACNA1S in the functional incompetence of adipose-derived mesenchymal stem cells by induced indoxyl sulfate in chronic kidney disease
Duyen Thi Do et al.
CYTOTECHNOLOGY (2016)
Million Veteran Program: A mega-biobank to study genetic influences on health and disease
John Michael Gaziano et al.
JOURNAL OF CLINICAL EPIDEMIOLOGY (2016)
Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function
Jiaojiao Jing et al.
KIDNEY INTERNATIONAL (2016)
Genomics is failing on diversity
Alice B. Popejoy et al.
NATURE (2016)
A reference panel of 64,976 haplotypes for genotype imputation
Shane McCarthy et al.
NATURE GENETICS (2016)
Insights into kidney diseases from genome-wide association studies
Matthias Wuttke et al.
NATURE REVIEWS NEPHROLOGY (2016)
GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS
Anselm S. Hoppmann et al.
PLOS ONE (2016)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro et al.
NATURE COMMUNICATIONS (2016)
Chronic kidney disease and cardiovascular risk in six regions of the world (ISN-KDDC): a cross-sectional study
Bogdan Ene-Iordache et al.
LANCET GLOBAL HEALTH (2016)
The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany
Markus Loeffler et al.
BMC PUBLIC HEALTH (2015)
Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci
Holger Kirsten et al.
HUMAN MOLECULAR GENETICS (2015)
The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary results
Cristian Pattaro et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management-A KDIGO consensus report
Kai-Uwe Eckardt et al.
KIDNEY INTERNATIONAL (2015)
Partitioning heritability by functional annotation using genome-wide association summary statistics
Hilary K. Finucane et al.
NATURE GENETICS (2015)
An atlas of genetic correlations across human diseases and traits
Brendan Bulik-Sullivan et al.
NATURE GENETICS (2015)
Gene expression analysis identifies global gene dosage sensitivity in cancer
Rudolf S. N. Fehrmann et al.
NATURE GENETICS (2015)
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Brendan K. Bulik-Sullivan et al.
NATURE GENETICS (2015)
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality
Johannes Raffler et al.
PLOS GENETICS (2015)
Second-generation PLINK: rising to the challenge of larger and richer datasets
Christopher C. Chang et al.
GIGASCIENCE (2015)
SNiPA: an interactive, genetic variant-centered annotation browser
Matthias Arnold et al.
BIOINFORMATICS (2015)
Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity
Nan Cher Yeo et al.
GENOME RESEARCH (2015)
Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies
Chengliang Dong et al.
HUMAN MOLECULAR GENETICS (2015)
The Landscape of Clinical Trials in Nephrology: A Systematic Review of ClinicalTrials.gov
Jula K. Inrig et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2014)
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality
Ilkka Seppala et al.
EUROPEAN HEART JOURNAL (2014)
Rare mutations associating with serum creatinine and chronic kidney disease
Gardar Sveinbjornsson et al.
HUMAN MOLECULAR GENETICS (2014)
Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of End-Stage Renal Disease and Mortality
Josef Coresh et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis
Matthias Olden et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
A general framework for estimating the relative pathogenicity of human genetic variants
Martin Kircher et al.
NATURE GENETICS (2014)
A Gene Variant in CERS2 Is Associated with Rate of Increase in Albuminuria in Patients with Diabetes from ONTARGET and TRANSCEND
Dov Shiffman et al.
PLOS ONE (2014)
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
Claudia Giambartolomei et al.
PLOS GENETICS (2014)
Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney
Hideyuki Motohashi et al.
AAPS JOURNAL (2013)
Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
Weijia Xie et al.
DIABETES (2013)
Common Variants in Mendelian Kidney Disease Genes and Their Association with Renal Function
Afshin Parsa et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)
Chronic kidney disease: global dimension and perspectives
Vivekanand Jha et al.
LANCET (2013)
Evolving importance of kidney disease: from subspecialty to global health burden
Kai-Uwe Eckardt et al.
LANCET (2013)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
Anna Koettgen et al.
NATURE GENETICS (2013)
Systematic identification of trans eQTLs as putative drivers of known disease associations
Harm-Jan Westra et al.
NATURE GENETICS (2013)
Estimating the Glomerular Filtration Rate in the General Population Using Different Equations: Effects on Classification and Association
Cristian Pattaro et al.
NEPHRON CLINICAL PRACTICE (2013)
GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data
Christian Fuchsberger et al.
BIOINFORMATICS (2012)
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function
Daniel I. Chasman et al.
HUMAN MOLECULAR GENETICS (2012)
Improved equations estimating GFR in children with chronic kidney disease using an immunonephelometric determination of cystatin C
George J. Schwartz et al.
KIDNEY INTERNATIONAL (2012)
An integrated map of genetic variation from 1,092 human genomes
David M. Altshuler et al.
NATURE (2012)
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations
Yukinori Okada et al.
NATURE GENETICS (2012)
The German Chronic Kidney Disease (GCKD) study: design and methods
Kai-Uwe Eckardt et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function
Cristian Pattaro et al.
PLOS GENETICS (2012)
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
Zari Dastani et al.
PLOS GENETICS (2012)
GCTA: A Tool for Genome-wide Complex Trait Analysis
Jian Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Rationale and Design of the Leipzig (LIFE) Heart Study: Phenotyping and Cardiovascular Characteristics of Patients with Coronary Artery Disease
Frank Beutner et al.
PLOS ONE (2011)
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
Rudolf S. N. Fehrmann et al.
PLOS GENETICS (2011)
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
William McLaren et al.
BIOINFORMATICS (2010)
METAL: fast and efficient meta-analysis of genomewide association scans
Cristen J. Willer et al.
BIOINFORMATICS (2010)
MCMC Methods for Multi-Response Generalized Linear Mixed Models: The MCMCglmm R Package
Jarrod D. Hadfield
JOURNAL OF STATISTICAL SOFTWARE (2010)
New loci associated with kidney function and chronic kidney disease
Anna Koettgen et al.
NATURE GENETICS (2010)
Genetic loci influencing kidney function and chronic kidney disease
John C. Chambers et al.
NATURE GENETICS (2010)
Genetics and Beyond - The Transcriptome of Human Monocytes and Disease Susceptibility
Tanja Zeller et al.
PLOS ONE (2010)
A New Equation to Estimate Glomerular Filtration Rate
Andrew S. Levey et al.
ANNALS OF INTERNAL MEDICINE (2009)
Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity
K. K. Filipski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)
Bayes Factors for Genome-Wide Association Studies: Comparison with P-values
Jon Wakefield
GENETIC EPIDEMIOLOGY (2009)
Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas
Silke Imgrund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Targeted Disruption of the Multidrug and Toxin Extrusion 1 (Mate1) Gene in Mice Reduces Renal Secretion of Metformin
Masahiro Tsuda et al.
MOLECULAR PHARMACOLOGY (2009)
Multiple loci associated with indices of renal function and chronic kidney disease
Anna Koettgen et al.
NATURE GENETICS (2009)
PLINK: A tool set for whole-genome association and population-based linkage analyses
Shaun Purcell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
A Bayesian measure of the probability of false discovery in genetic epidemiology studies
Jon Wakefield
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
A new multipoint method for genome-wide association studies by imputation of genotypes
Jonathan Marchini et al.
NATURE GENETICS (2007)
Clustering by passing messages between data points
Brendan J. Frey et al.
SCIENCE (2007)
The kallikrein-kinin system: Current and future pharmacological targets
ME Moreau et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
AS Go et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Quantifying heterogeneity in a meta-analysis
JPT Higgins et al.
STATISTICS IN MEDICINE (2002)
The organic cation transporter OCT2 mediates the uptake of β-adrenoceptor antagonists across the apical membrane of renal LLC-PK1 cell monolayers
AJ Dudley et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)