期刊
NATURAL PRODUCT RESEARCH
卷 35, 期 6, 页码 993-999出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2019.1610755
关键词
Mentha spicata L; Mentha pulegium L; essential oil; antifungal activity; Candida albicans
This study evaluated the antifungal activity of Mentha spicata L. and Mentha pulegium L. from Sardinia, finding that the essential oils were effective against various fungal strains, including Candida albicans. The oils were particularly efficient in inhibiting germ tube formation of C. albicans.
This study aims to evaluate the antifungal activity of Mentha spicata L. and Mentha pulegium L. from Sardinia and to assess their efficacy on virulence factors for Candida albicans, particularly on the inhibition of the germ tube formation. The major compounds of the essential oils were carvone (62.9%) for M. spicata and pulegone (86.2%) for M. pulegium. The essential oil from M. spicata showed a more preeminent effect against Cryptococcus neoformans and the dermatophytes Trichophyton rubrum and T. verrucosum (0.32 mu L/mL). Both oils were very effective in inhibiting C. albicans germ tube formation, at doses well below their MIC (0.16 mu L/mL).
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