Aristololactam alkaloids from the roots of Dasymaschalon rostratum

A novel aristololactam alkaloid, dasymalactam A (1), together with nine known analogues (2-10), were isolated from the roots of Dasymaschalon rostratum. Their structures were elucidated by IR, NMR and MS spectrums and comparisons with data reported in the literature. All compounds demonstrated weak cytotoxicity against Hela, MCF-7, A-549, MGC-803, and COLO-205 human cancer cell lines. [GRAPHICS] .

Automated summary

A novel aristololactam alkaloid, dasymalactam A, and nine known analogues were isolated from Dasymaschalon rostratum roots. These compounds demonstrated weak cytotoxicity against several human cancer cell lines.