相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cyclodextrin-Drug Inclusion Complexes: In Vivo and In Vitro Approaches
Simone Braga Carneiro et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers
Almudena Perez-Sanchez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Phyto-phospholipid complexes (phytosomes): A novel strategy to improve the bioavailability of active constituents
Mei Lu et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers
Zongmin Zhao et al.
ADVANCED DRUG DELIVERY REVIEWS (2019)
Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Preparation and in vitro characterization
Abid Mehmood Yousaf et al.
JOURNAL OF PHARMACEUTICAL ANALYSIS (2019)
Characterization of magnetite nanoparticles synthetized from Fe(II)/nitrate solutions for arsenic removal from water
Erika Di Iorio et al.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2019)
Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin
Carola Diaz et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2018)
Surface Functionalization and Targeting Strategies of Liposomes in Solid Tumor Therapy: A Review
Muhammad Kashif Riaz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Silymarin loaded nanostructured lipid carrier: From design and dermatokinetic study to mechanistic analysis of epidermal drug deposition enhancement
Babar Iqbal et al.
JOURNAL OF MOLECULAR LIQUIDS (2018)
Application of Spray Drying Particle Engineering to a High-Functionality/Low-Solubility Milk Thistle Extract: Powders Production and Characterization
Francesca Sansone et al.
MOLECULES (2018)
Self-assembly and directed assembly of lipid nanocarriers for prevention of liver fibrosis in obese rats: a comparison with the therapy of bariatric surgery
Chun-Han Chen et al.
NANOMEDICINE (2018)
Protective capabilities of silymarin and inulin nanoparticles against hepatic oxidative stress, genotoxicity and cytotoxicity of Deoxynivalenol in rats
Mosaad A. Abdel-Wahhab et al.
TOXICON (2018)
Nanostructured Lipid Carriers as Promising Delivery Systems for Plant Extracts: The Case of Silymarin
Vieri Piazzini et al.
APPLIED SCIENCES-BASEL (2018)
Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases
Ludovico Abenavoli et al.
PHYTOTHERAPY RESEARCH (2018)
Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra et al.
JOURNAL OF NANOBIOTECHNOLOGY (2018)
Enhancement of Silymarin Anti-fibrotic Effects by Complexation With Hydroxypropyl (HPBCD) and Randomly Methylated (RAMEB) β-Cyclodextrins in a Mouse Model of Liver Fibrosis
Sami Gharbia et al.
FRONTIERS IN PHARMACOLOGY (2018)
Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: applications, advantages and disadvantages
Parisa Ghasemiyeh et al.
RESEARCH IN PHARMACEUTICAL SCIENCES (2018)
撤稿声明: Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line (Retraction of Vol 3, Pg 67, 2013)
Zohreh Ebrahimnezhad et al.
BIOIMPACTS (2018)
Highly bioavailable silibinin nanoparticles inhibit HCV infection
Ching-Hsuan Liu et al.
GUT (2017)
A new drug nanocrystal self-stabilized Pickering emulsion for oral delivery of silybin
Tao Yi et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Non-covalent formulation of active principles with dendrimers: Current state-of-the-art and prospects for further development
Igor Elkin et al.
JOURNAL OF CONTROLLED RELEASE (2017)
Quality by design based silymarin nanoemulsion for enhancement of oral bioavailability
Amrita Nagi et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2017)
Silybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)-Chemistry, Bioavailability, and Metabolism
Michal Bijak
MOLECULES (2017)
In vivo fate of lipid-silybin conjugate nanoparticles: Implications on enhanced oral bioavailability
Yuhua Ma et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)
Prediction of Permeation and Cellular Transport of Silybum marianum Extract Formulated in a Nanoemulsion by Using PAMPA and Caco-2 Cell Models
Vieri Piazzini et al.
PLANTA MEDICA (2017)
Fabrication, characterization and in vitro evaluation of silibinin nanoparticles: an attempt to enhance its oral bioavailability
Muhammad Umar Khayam Sahibzada et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2017)
In Vivo Fate of Biomimetic Mixed Micelles as Nanocarriers for Bioavailability Enhancement of Lipid Drug Conjugates
Yuhua Ma et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
In Vivo Fate of Biomimetic Mixed Micelles as Nanocarriers for Bioavailability Enhancement of Lipid Drug Conjugates
Yuhua Ma et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
In vivo fate of lipid-based nanoparticles
Jianping Qi et al.
DRUG DISCOVERY TODAY (2017)
Improved hepatoprotective activity of silymarin via encapsulation in the novel vesicular nanosystem bilosomes
Amira Mohamed Mohsen et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2017)
Cancer nanomedicine: a review of recent success in drug delivery
Stephanie Tran et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2017)
Silymarin-Loaded Eudragit Nanoparticles: Formulation, Characterization, and Hepatoprotective and Toxicity Evaluation
Amira E. El-Nahas et al.
AAPS PHARMSCITECH (2017)
Delivering natural products and biotherapeutics to improve drug efficacy
Mohammad A. Obeid et al.
THERAPEUTIC DELIVERY (2017)
Improving the water solubility and antimicrobial activity of silymarin by nanoencapsulation
Ji-Soo Lee et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2017)
In Vitro Release and Bioavailability of Silybin from Micelle-Templated Porous Calcium Phosphate Microparticles
Yuan Zhu et al.
AAPS PHARMSCITECH (2016)
Synchronous microencapsulation of multiple components in silymarin into PLGA nanoparticles by an emulsification/solvent evaporation method
Yunchang Xie et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2016)
Silymarin-loaded Eudragit® RS100 nanoparticles improved the ability of silymarin to resolve hepatic fibrosis in bile duct ligated rats
N. Younis et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
A supersaturating delivery system of silibinin exhibiting high payload achieved by amorphous nano-complexation with chitosan
Minh-Hiep Nguyen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Inorganic Nanomaterials as Carriers for Drug Delivery
Shizhu Chen et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2016)
Phytoliposome-Based Silibinin Delivery System as a Promising Strategy to Prevent Hepatitis C Virus Infection
Maria Ripoli et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2016)
Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting
Yanni Ma et al.
MOLECULES (2016)
Formulation and clinical evaluation of silymarin pluronic-lecithin organogels for treatment of atopic dermatitis
Fatma M. Mady et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2016)
Silymarin nanoparticles through emulsion solvent evaporation method for oral delivery with high antioxidant activities, bioavailability, and absorption in the liver
Xiuhua Zhao et al.
RSC ADVANCES (2016)
Preparation and performance evaluation of emulsomes as a drug delivery system for silybin
Xiaodan Zhou et al.
ARCHIVES OF PHARMACAL RESEARCH (2015)
Drug nanosuspensions: a ZIP tool between traditional and innovative pharmaceutical formulations
Federica Leone et al.
EXPERT OPINION ON DRUG DELIVERY (2015)
A comparative study on the therapeutic effects of Silymarin and Silymarin-Loaded Solid Lipid Nanoparticles on D-GaIN/TNF-α-induced Liver Damage in Balb/c Mice
Mustafa Cengiz et al.
FOOD AND CHEMICAL TOXICOLOGY (2015)
A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals
Zheng Li et al.
FOOD HYDROCOLLOIDS (2015)
Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo
Gang Yang et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)
Comparison of the oral bioavailability of silymarin-loaded lipid nanoparticles with their artificial lipolysate counterparts: implications on the contribution of integral structure
Mingzhu Shangguan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Development, optimization and evaluation of long chain nanolipid carrier for hepatic delivery of silymarin through lymphatic transport pathway
Shilpa Chaudhary et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Polyethylene Sebacate-Silymarin Nanoparticles with Enhanced Hepatoprotective Activity
Swati A. Guhagarkar et al.
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2015)
Nanoemulsions as delivery systems of hydrophobic silybin from silymarin extract: Effect of oil type on silybin solubility, in vitro bioaccessibility and stability
Sonia Calligaris et al.
LWT-FOOD SCIENCE AND TECHNOLOGY (2015)
Nanostructured calcium phosphate carriers for deliver of poor water-soluble drug silybin
Lei Chen et al.
MATERIALS LETTERS (2015)
Investigation of the Interactions of Silibinin with 2-Hydroxypropyl-β-cyclodextrin through Biophysical Techniques and Computational Methods
Tahsin F. Kellici et al.
MOLECULAR PHARMACEUTICS (2015)
Nano-silymarin provides protection against γ-radiation-induced oxidative stress in cultured human embryonic kidney cells
Manish Adhikari et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2015)
Metabolic fingerprinting to understand therapeutic effects and mechanisms of silybin on acute liver damage in rat
Qun Liang et al.
PHARMACOGNOSY MAGAZINE (2015)
Laser light triggered smart release of silibinin from a PEGylated-PLGA gold nanocomposite
E. Fazio et al.
JOURNAL OF MATERIALS CHEMISTRY B (2015)
Improved dissolution and bioavailability of silymarin delivered by a solid dispersion prepared using supercritical fluids
Gang Yang et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugs
Saba Khan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2015)
Simultaneous diagnosis and drug delivery by silymarin-loaded magnetic nanoparticles
M. Khalkhali et al.
NANOMEDICINE JOURNAL (2015)
Fabrication, characterization and bioevaluation of silibinin loaded chitosan nanoparticles
Deep Pooja et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)
Nanotechnology-based drug delivery systems and herbal medicines: a review
Bruna Vidal Bonifacio et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)
Phyto-liposomes as nanoshuttles for water-insoluble silybin-phospholipid complex
Ruggero Angelico et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Binary lipids-based nanostructured lipid carriers for improved oral bioavailability of silymarin
Mingzhu Shangguan et al.
JOURNAL OF BIOMATERIALS APPLICATIONS (2014)
Recent Advances in the Nanotechnology-Based Drug Delivery of Silybin
Yancai Wang et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)
Silymarin Encapsulated Poly(D,L-lactic-co-glycolic acid) Nanoparticles: A Prospective Candidate for Prostate Cancer Therapy
K. S. Snima et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)
A novel solid dispersion system for natural product-loaded medicine: silymarin-loaded solid dispersion with enhanced oral bioavailability and hepatoprotective activity
Du Hyeong Hwang et al.
JOURNAL OF MICROENCAPSULATION (2014)
Measurement and correlation of solubility of bioactive compound silymarin in five different green solvents at 298.15 K to 333.15 K
Faiyaz Shakeel et al.
JOURNAL OF MOLECULAR LIQUIDS (2014)
Characterization and In Vitro Sustained Release of Silibinin from pH Responsive Carbon Nanotube-Based Drug Delivery System
Julia M. Tan et al.
JOURNAL OF NANOMATERIALS (2014)
Enhanced cytotoxicity and apoptosis-induced anticancer effect of silibinin-loaded nanoparticles in oral carcinoma (KB) cells
M. Gohulkumar et al.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2014)
Bioavailability of silymarin flavonolignans: drug formulations and biotransformation
Eleni Theodosiou et al.
PHYTOCHEMISTRY REVIEWS (2014)
Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells
Nitesh Kumar et al.
PHARMACOLOGICAL REPORTS (2014)
Microfluidic fabrication of silybin nanodispersion with high dissolution rate and tunable sizes
Gai-Jing Cui et al.
CHEMICAL ENGINEERING JOURNAL (2013)
Silymarin loaded liposomes for hepatic targeting: In vitro evaluation and HepG2 drug uptake
Mohammed Elmowafy et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Seventy-two-hour release formulation of the poorly soluble drug silybin based on porous silica nanoparticles: In vitro release kinetics and in vitro/in vivo correlations in beagle dogs
Xia Cao et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells
Silvia Cufi et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation
Kwan Yeol Yang et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2013)
Synchronized and controlled release of multiple components in silymarin achieved by the osmotic release strategy
Yunchang Xie et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Mathematical modeling of drug dissolution
J. Siepmann et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS
Pengfei Xu et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Characterization of the Solutol® HS15/water phase diagram and the impact of the Δ9-tetrahydrocannabinol solubilization
Sergio Murgia et al.
JOURNAL OF COLLOID AND INTERFACE SCIENCE (2013)
HiFSA Fingerprinting Applied to Isomers with Near-Identical NMR Spectra: The Silybin/Isosilybin Case
Jose G. Napolitano et al.
JOURNAL OF ORGANIC CHEMISTRY (2013)
Preparation, Characterisation and In Vivo Evaluation of Silybin Nanoparticles for the Treatment of Liver Fibrosis
Chandrasekhar R. Bonepally et al.
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2013)
Formulation of Microemulsion Systems for Dermal Delivery of Silymarin
Vipaporn Panapisal et al.
AAPS PHARMSCITECH (2012)
Oral bioavailability of silymarin formulated as a novel 3-day delivery system based on porous silica nanoparticles
Xia Cao et al.
ACTA BIOMATERIALIA (2012)
Preparation and Pharmacological Evaluation of Silibinin Liposomes
Hitesh Maheshwari et al.
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH (2012)
Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS)
Yinghui Wei et al.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2012)
Self-Emulsifying Drug Delivery Systems (SEDDS): Formulation Development, Characterization, and Applications
Bhupinder Singh et al.
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2012)
In vitro release and in vitro-in vivo correlation for silybin meglumine incorporated into hollow-type mesoporous silica nanoparticles
Xia Cao et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)
In Vivo Evaluation of Silybin Nanosuspensions Targeting Liver
Yancai Wang et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2012)
Emulsomes: An emerging vesicular drug delivery system
Bhawandeep Gill et al.
ASIAN JOURNAL OF PHARMACEUTICS (2012)
Silymarin Glyceryl Monooleate/Poloxamer 407 Liquid Crystalline Matrices: Physical Characterization and Enhanced Oral Bioavailability
Ruyue Lian et al.
AAPS PHARMSCITECH (2011)
Mixed micelles loaded with silybin-polyene phosphatidylcholine complex improve drug solubility
Rui-ling Duan et al.
ACTA PHARMACOLOGICA SINICA (2011)
Proliposomes for oral delivery of dehydrosilymarin: preparation and evaluation in vitro and in vivo
Chang Chu et al.
ACTA PHARMACOLOGICA SINICA (2011)
In vitro antitumor activity of silybin nanosuspension in PC-3 cells
Dandan Zheng et al.
CANCER LETTERS (2011)
Biodegradable pH-responsive alginate-poly (lactic-co-glycolic acid) nano/micro hydrogel matrices for oral delivery of silymarin
Ibrahim M. El-Sherbiny et al.
CARBOHYDRATE POLYMERS (2011)
Carbon Nanotubes as an Advanced Drug and Gene Delivery Nanosystem
Jafar Ezzati Nazhad Dolatabadi et al.
Current Nanoscience (2011)
Polyamidoamine dendrimers as potential drug carriers for enhanced aqueous solubility and oral bioavailability of silybin
Xin Huang et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2011)
Oil based nanocarrier for improved oral delivery of silymarin: In vitro and in vivo studies
Rabea Parveen et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)
Preparation and effects of 2,3-dehydrosilymarin, a promising and potent antioxidant and free radical scavenger
Shanshan Tong et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2011)
Silybin and the liver: From basic research to clinical practice
Carmela Loguercio et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Preparation and Evaluation of Silymarin β-cyclodextrin Molecular Inclusion Complexes
A. Ghosh et al.
JOURNAL OF YOUNG PHARMACISTS (2011)
Development of Silymarin Self-Microemulsifying Drug Delivery System with Enhanced Oral Bioavailability
Xinru Li et al.
AAPS PHARMSCITECH (2010)
Silymarin-solid dispersions: Characterization and influence of preparation methods on dissolution
Dalwadi Sonali et al.
ACTA PHARMACEUTICA (2010)
Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles
Jiang-nan Yu et al.
ACTA PHARMACOLOGICA SINICA (2010)
Preparation and In Vitro Evaluation of Povidone-Sodium Cholate-Phospholipid Mixed Micelles for the Solubilization of Poorly Soluble Drugs
Yuan Zhu et al.
ARCHIVES OF PHARMACAL RESEARCH (2010)
Nanostructured lipid carriers for parenteral delivery of silybin: Biodistribution and pharmacokinetic studies
Lejiao Jia et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2010)
Preparation and characterization of silybin-loaded nanostructured lipid carriers
Le-Jiao Jia et al.
DRUG DELIVERY (2010)
Antioxidant and antiviral activities of silybin fatty acid conjugates
Radek Gazak et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Supramolecular phospholipids-polyphenolics interactions: The PHYTOSOME® strategy to improve the bioavailability of phytochemicals
Ajay Semalty et al.
FITOTERAPIA (2010)
In vitro and in vivo evaluation of silybin nanosuspensions for oral and intravenous delivery
Yancai Wang et al.
NANOTECHNOLOGY (2010)
Milk Thistle in Liver Diseases: Past, Present, Future
Ludovico Abenavoli et al.
PHYTOTHERAPY RESEARCH (2010)
Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling
Rana R. Singh et al.
CLINICAL CANCER RESEARCH (2009)
Micronization of silybin by the emulsion solvent diffusion method
Zhi-Bing Zhang et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)
Interaction of milk-thistle-fruit flavanonols with Langmuir monolayers of lecithin and bilayers of liposomes
V. A. Kurkin et al.
PHARMACEUTICAL CHEMISTRY JOURNAL (2009)
Enhanced dissolution of silymarin/polyvinylpyrrolidone solid dispersion pellets prepared by a one-step fluid-bed coating technique
Ningyun Sun et al.
POWDER TECHNOLOGY (2008)
Analysis of silibinin in rat plasma and bile for hepatobiliary excretion and oral bioavailability application
Jhy-Wen Wu et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2007)
Preparation and characterization of solid lipid nanoparticles containing Silibinin
J. Q. Zhang et al.
DRUG DELIVERY (2007)
Estimating drug solubility in the gastrointestinal tract
J. B. Dressman et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Solubility of silybin in aqueous hydrochloric acid solution
Tong-Chun Bai et al.
FLUID PHASE EQUILIBRIA (2007)
Preparation, pharmacokinetics and body distribution of silymarin-loaded solid lipid nanoparticles after oral administration
Jun He et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2007)
Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system
Cheng Lu et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2007)
Analysis and comparison of active constituents in commercial standardized silymarin extracts by liquid chromatography-electrospray ionization mass spectrometry
James I. Lee et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients
Thomas W. Flaig et al.
INVESTIGATIONAL NEW DRUGS (2007)
Formulation and biopharmaceutical evaluation of silymarin using SMEDDS
Jong Soo Woo et al.
ARCHIVES OF PHARMACAL RESEARCH (2007)
Silybin and silymarin - New and emerging applications in medicine
Radek Gazak et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance
Mohamed S. El-Samaligy et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Preparation of silymarin proliposome: A new way to increase oral bioavailability of silymarin in beagle dogs
Xiao Yan-yu et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system
Wei Wu et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2006)
Solubility of silybin in aqueous poly(ethylene glycol) solution.
TC Bai et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Increasing bioavailability of silymarin using a buccal liposomal delivery system: Preparation and experimental design investigation
MS El-Samaligy et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
The preparation of silybin-phospholipid complex and the study on its pharmacokinetics in rats
YY Xiao et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Formulation, characterization, and in vitro evaluation of silymarin-loaded lipid microspheres
S Abrol et al.
DRUG DELIVERY (2004)
Oxidised derivatives of silybin and their antiradical and antioxidant activity
R Gazák et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, isolated from Silybum marianum (milk thistle)
DYW Lee et al.
JOURNAL OF NATURAL PRODUCTS (2003)
Analysis of the active components of silymarin
F Kvasnicka et al.
JOURNAL OF CHROMATOGRAPHY A (2003)
Determination of active component in silymarin by RP-LC and LC/MS
TM Ding et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2001)