4.5 Review

Ultrasound-assisted synthesis of heterocyclic compounds

期刊

MOLECULAR DIVERSITY
卷 24, 期 3, 页码 771-820

出版社

SPRINGER
DOI: 10.1007/s11030-019-09964-1

关键词

Ultrasonic irradiation (US); Heterocyclic compounds; Five-membered rings; Six-membered rings; Fused heterocycles; Spiro-compounds

资金

  1. Research Council of Alzahra University

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In this review, we tried to underscore the synthesis of the heterocyclic compounds under assisted ultrasonic irradiation. The ultrasonic irradiation has been applied for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes. Also, ultrasonic irradiation provides lower cost, excellent yields, greater purity, and simple workups as compared to lower yields, longer reaction times, lesser purity and in the conventional methods. In this review, we have compared synthesis of the heterocyclic compounds under ultrasonic irradiation with other methods. [GRAPHICS] .

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