4.7 Article

One-step synthesis of acriflavine-based carbon dots for adenine detection and a theoretical study on the detection mechanism

期刊

MICROCHEMICAL JOURNAL
卷 148, 期 -, 页码 73-78

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ELSEVIER
DOI: 10.1016/j.microc.2019.04.041

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资金

  1. National Key Research and Development Program of China [2017YFF0108600, 2017YFC0211900, 2016YFF0103800]
  2. National Natural Science Foundation of China [81771982, 61535010, 81771929, 21803075, 8160071152]
  3. Key Research Program of the Chinese Academy of Sciences [KFZD-SW-210]
  4. Natural Science Foundation of Jiangsu Province [BE2015601]
  5. Science and Technology Department of Suzhou City [SS201539, ZXY201434]

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Adenine detection is important in biomedicine. Here, we report acriflavine-based carbon dots prepared via a one-step synthesis that can detect adenine in aqueous solution via fluorescence. Titration experiments show that the fluorescence intensity of carbon dots increases by up to 35% as the concentration of adenine increnses. High-resolution transmission electron microscopy images show that carbon dots have a recognizable lattice structure. Based on this, we built a theoretical model using the DFT method to explain the mechanism by which adenine enhances fluorescence on the carbon dots.

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