期刊
MARINE DRUGS
卷 17, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/md17070408
关键词
marine biosurfactants; structural diversity; glycolipids; lipopeptides; oil degradation; biotechnological application; biosynthetic mechanisms; heterologous expression; synthetic biology
资金
- Ministry of Culture and Science of the German State of North Rhine-Westphalia [313/323-400-00213]
- European Union [634486]
- ERA-IB 5 'METACAT' [ERA-IB-14-030]
Biosurfactants are amphiphilic secondary metabolites produced by microorganisms. Marine bacteria have recently emerged as a rich source for these natural products which exhibit surface-active properties, making them useful for diverse applications such as detergents, wetting and foaming agents, solubilisers, emulsifiers and dispersants. Although precise structural data are often lacking, the already available information deduced from biochemical analyses and genome sequences of marine microbes indicates a high structural diversity including a broad spectrum of fatty acid derivatives, lipoamino acids, lipopeptides and glycolipids. This review aims to summarise biosyntheses and structures with an emphasis on low molecular weight biosurfactants produced by marine microorganisms and describes various biotechnological applications with special emphasis on their role in the bioremediation of oil-contaminated environments. Furthermore, novel exploitation strategies are suggested in an attempt to extend the existing biosurfactant portfolio.
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