期刊
MACROMOLECULAR BIOSCIENCE
卷 19, 期 10, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201900194
关键词
acrylate; catechol; maleimide; Mucoadhesion; mucoadhesive polymers; thiomers; water-soluble polymers
资金
- Leverhulme Trust [RPG-2013-017]
Mucoadhesion is defined as the adherence of a synthetic or natural polymer to a mucosal membrane via physical or chemical interactions. Mucoadhesive materials are widely used to develop dosage forms for transmucosal drug delivery via ocular, nasal, esophageal, oral, vaginal, rectal, and intravesical routes of administration. This review will discuss some of the most prominent and recent synthetic methodologies employed to modify polymeric materials in order to enhance their mucoadhesive properties. This includes chemical conjugation of polymers with molecules bearing thiol-, catechol-, boronate-, acrylate-, methacrylate-, maleimide-, and N-hydroxy(sulfo)succinimide ester- groups.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据