期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 141, 期 24, 页码 9527-9532出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.9b04711
关键词
-
资金
- NSFC [21525208, U1804283]
- Henan Normal University [5101034011009]
- Central Plains Scholars and Scientists Studio Fund [2018002]
Enantiomeric access to pentatomic biaryls is challenging due to their relatively low rotational barrier. Reported herein is the mild and highly enantioselective synthesis of 2,3'-biindolyls via underexplored integration of C-H activation and alkyne cyclization using a unified chiral Rh(III) catalyst. The reaction proceeded via initial C-H activation followed by alkyne cyclization. A chiral rhodacyclic intermediate has been isolated from stoichiometric C-H activation, which offers direct mechanistic insight.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据