4.7 Article

Palladium-Catalyzed Decarbonylative Suzuki-Miyaura Coupling of Amides To Achieve Biaryls via C-N Bond Cleavage

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 84, 期 17, 页码 10559-10568

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AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b01103

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资金

  1. Science and Technology Planning Project of Guangdong Province [2017A010103017]
  2. Special Innovation Projects of Common Universities in Guangdong Province [20178S0182]
  3. National Natural Science Foundation of China [51703069]

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The palladium-catalyzed decarbonylative Suzuki-Miyaura coupling of amides via selective amide C-N bond cleavage was reported, which afforded mild access to substitute biaryl products in the presence of low catalyst loading with NaHCO3 as the base in good yields within 4 h (29 examples).

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