期刊
JOURNAL OF NATURAL PRODUCTS
卷 82, 期 7, 页码 1831-1838出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.9b00062
关键词
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资金
- CNPq [420454/2016-0, 309060/2016-8]
- CAPES/FUNCAP [88887.113263/2015-01]
- INCT BioNat [465637/2014-0]
- FAPESP [2015/17177-6, 2014/50926-0]
Salinaphthoquinones A-E (1-5) were isolated from a marine Salininispora arenicola strain, recovered from sediments of the St. Peter and St. Paul Archipelago, Brazil. The structures of the compounds were elucidated using a combination of spectroscopic (NMR, IR, HRESIMS) data, including single-crystal X-ray diffraction analysis. A plausible biosynthetic pathway for 1-5 is proposed. Compounds 1 to 4 displayed moderate activity against Staphylococcus aureus and Enterococcus faecalis with MIC values of 125 to 16 mu g/mL.
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