Synthesis, structural investigations and in vitro biological evaluation of N, N-dimethyl aniline derivatives based azo dyes as potential pharmacological agents

Three novel bioactive azo dyes were synthesized by a classical diazo-coupling method using sulfame-thazine with three different N, N-dimethyl aniline derivatives as coupling components under appropriate experimental conditions. The structural features of the newly synthesized compounds were explored by using various analytical and spectroscopic techniques. Further, these compounds were assessed for the different pharmacological activities such as antimicrobial, anti-tuberculosis, antioxidant and anti-inflammatory properties and results indicated that, these azo compounds exhibited effective pharmacological activities. (C) 2019 Elsevier B.V. All rights reserved.