期刊
JOURNAL OF MICROBIOLOGICAL METHODS
卷 162, 期 -, 页码 28-37出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mimet.2019.05.001
关键词
Probiotics; Dermatophytes; Candida albicans; Aspergillus spp.; Methods
资金
- National Natural Science Foundation of China [81301703]
- Natural Science Foundation of Heilongjiang Province, China [QC2013C078]
- Chinese Government (CSC) Scholarship [2016BSZ783]
- Government of Kenya under The Technical University of Kenya
Fungal burden throughout the world is very high and it keeps escalating due to increasing numbers of immunocompromised individuals. In contrast, the drugs used in management of fungal infections are so few some with high toxicity. Furthermore, highly resistant fungal pathogens are emerging for example Candida auris, Candida glabrata, Candida gullemondii and Aspergillus species among others. Thus now, more than ever, there is a need for combined efforts and an all round search for possible solutions to curb these problems. Therefore, the role of probiotics in management of fungal infections is indispensable. In fact, the antimicrobial activity of probiotics has been screened with promising results against microbial pathogens. Although, recent reports indicated that probiotics may also contribute to protect against fungal infections, the research done in checking antifungal activity of probiotics has used varied technology. This calls for harmonization of the methods used to screen and confirm the antimicrobial activity of probiotics and other candidate microorganisms. We therefore sought to address issues of disparity in probiotic research and their outcomes. Thus this paper is in order as it comprehensively reviews' publications, provides a summary of the methods and future prospects of probiotics as antifungal agents.
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